Fast and slow chemical signalling in the nervous system

著者

    • Goodman, E. C. (Elisabeth C.)
    • Neuroscience Research Centre (Merck Sharp & Dohme)

書誌事項

Fast and slow chemical signalling in the nervous system

edited by L.L. Iversen and E.C. Goodman

(Oxford medical publications)

Oxford University Press, 1986

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注記

"Proceedings of a symposium held in May 1985 to celebrate the inauguration of the Neuroscience Research Centre established by Merck Sharp & Dohme Research Laboratories in Harlow, England"--Introd

Includes bibliographies and index

内容説明・目次

内容説明

The modulatory actions of neuropeptides and amines are described in this volume, and compared with new knowledge about L-glutamic acid and gamma-aminobutyric acid (GABA), the principle fast chemical neurotransmitters in the mammalian brain. Also discussed are the changes in the way in which chemical signalling is viewed, following the discovery that multiple chemical signals may be secreted by single nerve cells.

目次

  • L L Iversen: Introduction
  • AMINO ACIDS AS FAST SIGNALS: K Krnjevi 'c: Amino acid transmitters: 30 years' progress in research
  • J L Barker, B Dufy & R N McBurney: Amino acid and peptide signals in cultured CNS neurons and clonal pituitary cells
  • J S Kelly, V Crunelli, S Forda, N Leresche & M Pirchio: Fast synaptic responses in the hippocampus and dorsal lateral geniculate nucleus of the rat
  • A M Sillito: Fast and slow chemical signalling in the visual cortex: an evaluation of GABA- and neuropeptide-mediated influences
  • P Krogsgaard-Larsen, L Nielsen, U Madsen & E Nielsen: GABA and glutamic acid agonists of pharmacological interest
  • J C Watkins: Selective antagonists define sub-classes of excitatory amino acid receptors
  • S H Snyder: Multiple benzodiazepine and related receptors as targets for psychotropic drug action
  • E H F Wong & J Kemp: Amino acids as fast signals: discussion
  • NEUROPEPTIDES AND MONOAMINES AS SLOW SIGNALS: G N Woodruff: Receptors and second messengers for neuropeptides and monoamines
  • D A Brown: Voltage-sensitive ion channels mediating modulatory effects of acetylcholine, amines, and peptides
  • S I Walaas, J K-T Wang & P Greengard: First messengers, second messengers, and protein phosphorylation in CNS
  • T M Jessell & C E Jahr: Synaptic interactions between dorsal root ganglion and dorsal horn neurons in cell culture: amino acids, nucleotides, and peptides as possible fast and slow excitatory transmitters
  • R F Irvine & M J Berridge: Inositude metabolism in the brain: its potential role in complex neuronal pathways
  • T H "okfelt et al: Coexistence of peptides and other active molecules in neurons: diversity of chemical signalling potential
  • S Freedman & K Watling: Neuropeptides and monoamines as slow signals: discussion
  • CHEMICALLY ADDRESSED NEURAL COMMUNICATIONS: F O Schmitt: Chemical information processing in the brain: prospect from retrospect
  • E A Kravitz: Serotonin, octopamine, and proctolin: two amines and a peptide, and aspects of lobster behaviour
  • W Sossin, T Kreiner & R H Scheller: Aplysia neurosecretory cells: multiple populations of dense core vesicles
  • D E Koshland Jr: Molecular mechanisms for memory
  • F E Bloom: Chemical signalling in the spatial, temporal continuum
  • J D Salamone & N G Bowery: Chemically addressed neural communications: discussion
  • Index.

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