書誌事項

Protein-nucleic acid interaction

edited by Wolfram Saenger and Udo Heinemann

(Topics in molecular and structural biology, v. 10)

Macmillan, 1989

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Protein-nucleic acid interactions have been a focal point of scientific interest and research over the past three decades. This volume contains a series of essays which describe a range of problems in the field, investigated by a variety of techniques. An introductory chapter on DNA-protein interactions in the regulation of gene expression is followed by papers on selected model systems. These cover several orders of magnitude in size, going from small proteins through Lac repressor headpiece and RNase T1 to chromatin. The aim of the text has been to reflect the diversity of problems even in this well-defined scientific field, and to provide researchers with all of the important techniques currently used to study the interactions.

目次

  • DNA-protein interactions in the regulation of gene expression, P.H.von Hippel and D.G.Berg
  • structures of protein-nucleic acid complexes in solution by electro-optical analysis, D.Porschke and J.Antosiewicz
  • NMR studies of protein-DNA recognition - the interaction of LAC repressor headpiece with repressor DNA, R.Kaptein et al
  • the single-stranded DNA binding protein of Escherichia coli, J.Greipel et al
  • protein-nucleic acid interactions in tobacco mosaic virus, G.Stubbs
  • structural and functional studies of ribonuclease T1, U.Heinemann and U.Hahn
  • Tet repressor - Tet operator interaction, W.Hillen and A.Wissmann
  • structure and condensation of chromatin, M.H.J.Koch.

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