Mechanisms of carcinogenesis
著者
書誌事項
Mechanisms of carcinogenesis
(Cancer growth and progression, v. 2)
Kluwer Academic Publishers, c1989
大学図書館所蔵 全8件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographies and index
内容説明・目次
内容説明
but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
目次
1. The influence of human behavior on neoplastic progression.- 2. The influence of stressors on the progression of neoplastic change.- 3. The seven types of causes of neoplastic growth - an organismic view.- 4. Chemoprevention research.- 5. Premalignant and non-invasive lesions of the urinary bladder.- 6. Species-specific aspects of the carcinogenicity of chloroform.- 7. Carcinogenic effects of ionizing radiation.- 8. Selected aspects of viral carcinogenesis.- 9. The quantum theory of carcinogenesis - a short review.- 10. Cellular oncogene activation by chromosomal translocation.- 11. Amplification of the oncogene N-Myc as a correlate to advanced stage in human neuroblastomas.- 12. Potential roles of activated proto-oncogenes in malignant progression.- 13. Oncogenes and their encoded products as targets for cancer therapy.- 14. Methods to study RAS oncogene-mediated induction of the metastatic phenotype.- 15. Oncogene products as potential therapeutic targets for control of established metastatic disease.- 16. Neoplastic cell stages and progression in experimental hepatocarcinogenesis.- 17. Characterization of eleven important transplantable murine tumors from the standpoint of morphology, pyrimidine biosynthesis and responsiveness to pyrimidine antimetabolites.- 18. Use of organ expiant and cell culture in cancer research.- 19. Season of operation and differential long-term progression: clinical, statistical, and psychological issues.- 20. Endogenous factors affecting the progression of carcinogen-induced rat mammary carcinomas.- 21. Age factors in the presence of selected neoplasms.- 22. Extremely low frequency electromagnetic fields as possible promotors of carcinogenesis.- 23. Medical geography and neoplasms.- Index of subjects.
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