Genetic analysis of tumour suppression
Author(s)
Bibliographic Information
Genetic analysis of tumour suppression
（Ciba Foundation symposium, 142）
Wiley, 1989
- Other Title
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Tumour suppression
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Proceedings of a symposium held at the Ciba Foundation, London, July 19-21, 1988
Editors, Greg Bock, Joan Marsh
"A Wiley-Interscience publication."
Includes bibliographies and indexes
Description and Table of Contents
Description
These papers on tumour suppression, given at a symposium held in London from 19-21 July 1988, cover the epidemiology and analysis of retinoblastoma (the best studied recessive human cancer), and the interaction of oncogenes and tumour suppressor genes both in differentiation and in tumourigenesis. Evidence for genetic information responsible for tumour repression comes from experiments on cell fusion, chromosome transfer, gene transfection and from classical genetics.
Table of Contents
Partial table of contents:. Epidemiology of Genetically Determined Cancer (A. Knudson). Reversion of Tumorigenicity in an EBV-Converted Burkitt's Lymphoma Line (G. Klein). Loss of Genetic Information in Cancer (W. Cavenee, et al.). Proviral Position Effects: Possible Probes for Genes That Suppress Transcription (J. Wyke, et al.). Flat Revertants of EJ Human Bladder Carcinoma Cells Show Two Different Mechanisms of Reversion (H. Patterson, et al.). A Genetic Basis for Tumor Suppression (E. Stanbridge). Suppression of Genetic Melanoma in the Fish Xiphophorus (M. Schwab). The Biology of Tumor Suppression (H. Harris). Cell Differentiation and Tumor Suppression (L. Sachs). Index of Contributors. Subject Index.
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