The mosaic of autoimmunity : (the factors associated with autoimmune disease )
著者
書誌事項
The mosaic of autoimmunity : (the factors associated with autoimmune disease )
（Research monographs in immunology, v. 12）
Elsevier , Sole distributors for the USA and Canada, Elsevier Science Pub. Co., 1989
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注記
Includes bibliographies and index
内容説明・目次
内容説明
This book comprehensively sets out the common aetiopathogenetic mechanisms shared by many, apparently diverse, diseases of the immune system. Unlike most other texts it does not emphasise the differences between autoimmune diseases, but establishes their many common links including hormonal effects, dietary and immunogenetic influences, complement deficiencies and environmental factors. Special attention is given to the effects of ageing and the relationship with malignancies. The scope of the book is very broad so as to cover the integration of the many diverse components which interact to cause autoimmunity, and it contains many 1988 and 1989 references and over 100 figures and tables, offering an attractive, up-to-date guide to modern concepts. It will greatly assist immunologists wishing to enter the field of autoimmunity, and will serve as an invaluable reference work for those already working in it.
目次
1. A Short History of Autoimmune Diseases 2. Autoimmune Diseases - Clinical Features and Animal Models 3. Natural Autoimmunity (i) Natural autoantibodies (ii) Autoantibodies in healthy populations 4. Analysis of the Components of the Immune System Involved in Autoimmunity (i) Immune complexes and antibody mediated damage (ii) Idiotype network (iii) Glycosylation studies: Analysis of abnormalities in the oligosaccharides attached to IgG (iv) T Suppressor cells (v) Natural killer cells 5. The genetic components of autoimmunity (i) Family studies (ii) Autoimmune disease and the major histocompatability complex (MHC/HLA) (iii) The Gm allotype system and autoimmune diseases (iv) Complement deficiency and autoimmunity (v) Immunodeficiency states and autoimmune conditions (vi) IgA deficiency and autoimmunity 6. Hormonal Components and Autoimmune Diseases (i) Sex steroids (ii) Autoimmunity and pregnancy (iii) Thymic hormones and autoimmunity (iv) The effect of corticosteroids on the immune system (v) Vitamin D, the immune system and autoimmunity (vi) Cytokines and autoimmunity 7. Environmental Factors and Autoimmunity (i) Drugs and autoimmunity (ii) Infection and autoimmunity (iii) Mycobacteria and autoimmunity (iv) HIV Infection and autoimmunity (v) Nutrition and autoimmunity (vi) Ultraviolet light and autoimmunity (vii) Toxins and chemicals (viii) Stress and autoimmunity 8. Ageing and autoimmunity 9. Cancer and autoimmunity (i) Malignancy in autoimmune conditions (ii) Autoimmune syndromes in cancer (iii) Autoantibodies in malignant diseases 10. Graft versus Host Disease and Autoimmunity 11. Treatment of the Autoimmune Diseases 12. Concluding Remarks: The Mosaic of Autoimmunity
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