Prostaglandins and related substances : a practical approach

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Bibliographic Information

Prostaglandins and related substances : a practical approach

Edited by C. Benedetto ... [et al.]

(The practical approach series)

IRL Press, c1987

  • : pbk.

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Includes index

Description and Table of Contents

Description

The eicosanoids--in particular the prostaglandins, thromboxanes and leukotrienes--have diverse and potent pharmacological effects that have excited the interest of medical and commercial researchers.

Table of Contents

  • Section I: Introduction and metabolism
  • Section II: Sampling and extraction
  • Section III: Physio-chemical methods
  • Section IV: Pharmacological and immunoassays
  • Section V: Enzymology and lipid peroxidation
  • Section VI: Related techniques
  • Appendix: Eicosanoids: structure, availability, storage and stability
  • Abbreviations
  • Introduction to the eicosanoids
  • Metabolism of prostaglandins and lipoxygenase products: relevance for eicosanoid assay
  • Tissue sampling and preparation
  • Extraction of eicosanoids from biological samples
  • Thin-layer chromatography (including radio thin-layer chromatography and autoradiography of prostaglandins and related compounds
  • High pressure liquid chromatography in the analysis of arachidonic acid metabolites
  • Gas chromatography and mass spectrometry of eicosanoids
  • Measurement of prostaglandins, thromboxanes and leukotrienes by smooth muscle bioassay
  • Aggregometry techniques for prostanoid study and evaluation
  • Radioimmunoassay of eicosanoids
  • Enzyme immunoassay
  • Cyclo-oxygenases: measurement, purification and properties
  • Lipoxygenases: measurement, characterization and properties
  • Lipid peroxidation
  • Quantitative measurement of arachidonic acid in tissues or fluids
  • Methods in prostanoid receptor classification
  • Paf-acether (platelet-activating factor)
  • Appendix
  • Index

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Details
  • NCID
    BA10056446
  • ISBN
    • 185221032X
    • 1852210311
  • Country Code
    uk
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Oxford
  • Pages/Volumes
    xix, 327 p.
  • Size
    23 cm
  • Parent Bibliography ID
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