Frontiers of NMR in molecular biology : proceedings of an Abbott Laboratories-UCLA Symposia Colloquium, held at Park City, Utah, January 12-19, 1989

書誌事項

Frontiers of NMR in molecular biology : proceedings of an Abbott Laboratories-UCLA Symposia Colloquium, held at Park City, Utah, January 12-19, 1989

editors, David Live, Ian M. Armitage, Dinshaw Patel

(UCLA symposia on molecular and cellular biology, new series ; v. 109)

Wiley-Liss, 1990

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注記

"1989 UCLA Colloquium, Frontiers of NMR in Molecular Biology"--Pref

Includes bibliographical references and index

内容説明・目次

内容説明

This volume examines the application of NMR techniques to molecular biology, including gene cloning and expression, site- specific mutagenesis, and biosynthetic isotopic labelling. It describes the broad-ranging applications of NMR techniques to the elucidation of structures at atomic resolution for moderately large systems. Investigators from a variety of disciplines cover the analysis of conformation, dynamics and interactions for a variety of molecules, including DNA, RNA, carbohydrates, peptides and proteins. Throughout the text, the contributors demonstrate the success of multi-dimensional NMR studies of biopolymers in solution. The book also examines possible NMR approaches for investigating systems where the molecule of interest does not reorient rapidly in solution. These systems possess molecules in the crystalline or hydrated solid state, part of supramolecular structures in solution, or are simply too large to reorient.

目次

  • Peptides and Peptide-Protein Interactions
  • Proteins
  • Carbohydrates
  • Nucleic Acids
  • Discussion Summaries.

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