Nucleic acid methylation : proceedings of a Hoffman-La Roche-UCLA Colloquium on Nucleic Acid Methylation held at Frisco, Colorado, March 31-April 7, 1989

書誌事項

Nucleic acid methylation : proceedings of a Hoffman-La Roche-UCLA Colloquium on Nucleic Acid Methylation held at Frisco, Colorado, March 31-April 7, 1989

editors, Gary A. Clawson ... [et al.]

(UCLA symposia on molecular and cellular biology, new ser., v. 128)

Wiley-Liss, c1990

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注記

"UCLA Symposia Colloquium on Nucleic Acid Methylation"--Pref

The Colloquium was sponsored by Hoffmann-La Roche, inc

Includes bibliographical references

Includes index

内容説明・目次

内容説明

Up-to-date research on the considerable advances made in the field of RNA and DNA modification is offered by this book. It assesses the developments in the capping and methylation of messenger RNA and examines the structure and function of ribosomal RNA methylation and its relevance to the structure of the ribosome. It features the exciting reports on DNA methylation in fungi and plants, genetic instability in Neurospora and the role of DNA methylation and the control of gene expression. The roles of DNA methylation in differentiation and tumorigenesis are discussed, with special emphasis on its potential in cell memory and the stabilization of transcriptionally incompetent states, particularly as they relate to silencing of the X chromosome.

目次

  • Ribosomal RNA Methylation
  • Capping Reactions
  • Function of RNA Methylation
  • DNA Methylation in Bacteria and Viruses
  • DNA Methylation in Plants
  • Inhibitors of DNA Methylation
  • Regulation of Gene Expression by DNA Methylation
  • Role of DNA Methylation in Imprinting.

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