Human psychopharmacology : measures and methods
著者
書誌事項
Human psychopharmacology : measures and methods
（A Wiley medical publication）
Wiley, c1987-
- v. 1
- v. 2
- v. 4
- v. 5
- v. 6
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注記
Includes bibliographies and index
内容説明・目次
- 巻冊次
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v. 1 ISBN 9780471912385
内容説明
One of the basic assumptions of the human psychopharmacologist is that the effects of psychoactive drugs can be judged by the changes they produce in human behaviour, whether in psychiatric patients or in healthy volunteers. The measurement of these changes to the disorders themselves often have to be made in subjects whose behaviour is not consistent. For example, circuadian variations, age, sex, personality, biological rhythms, motivation expectation and genetic predisposition are all capable of affecting behaviour. Assessment techniques must therefore be both sensitive and robust. This book brings together internationally respected researchers to discuss, within their own specialities, the use and development of test systems, the definition of research domains, the pragmatics of human experimentation, the application of experimental findings to therapeutics, the establishment of risk- benefit ratios and of appropriate measures whereby the efficacy and safety of modern psychopharmaceuticals can be assessed.
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v. 2 ISBN 9780471912552
内容説明
The second volume of a series of essays which examines the relationship between pharmacology and human psychiatry. Topics covered include drug evaluation in general practice, the limitations of psychiatric diagnosis in the management of chronic pain and clinical trials and assessments.
目次
- The measurement of retardation in depression, D.Widlocher and A.Ghozlan
- from animals to man - advantages, problems and pitfalls of animal models in psychopharmacology, B.E.Leonard
- the assessment of mood and its components, M.M.Robertson
- drug evaluation in general practice, G.Beaumont
- towards a clinical classification of antidepressant profiles, K.Siegfried
- memory assessment, D.M.Warburton and J.M.Rusted
- the human psychopharmacology of the methylxanthines, M.H.Lader and M.S.Bruce
- surgical and diagnostic procedures as models in psychopharmacology - assessment of pain and anxiety, C.A.O'Boyle and E.Fox
- the limitations of psychiatric diagnosis in the management of chronic pain, C.Feinmann and C.Bass
- the assessment of human sleep, T.J.Leigh
- clinical trials - rules and errors, A.Spriet and P.Simon
- clinical judgement - why and how to improve it, D.M.Chaput de Saintonge et al
- psychiatry in the 1990s - consensus of a report of a seminar held at Great Fosters Hotel, Egham, Surrey, February 1986, A.F.de Fonseca.
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v. 4 ISBN 9780471934110
内容説明
An analysis of an array of topics in human psychopharmacology, from the development of diagnostic scales and the use of neuro-imaging to the clinical assessment of dementia.
目次
- Partial table of contents:
- The Reliability, Validity and Pharmacosensitivity of Four Psychomotor Tests (N. Sherwood & J. Kerr)
- International Dementia Research: Comments on the Validation of Psychometric Measures and Proposals for the Definition of Clinical Relevance (H. Erzigkeit, et al.)
- CODE-DD: Development of a Diagnostic Scale for Depressive Disorders (T. Ban, et al.)
- The Contributions of Position Emission Tomography and Single-Photon Emission Computed Tomography Toward a Psychopharmacological Neuroanatomy of Obsessive-Compulsive Disorder (M. George)
- Psychopharmacology of Memory Components (H. Allain, et al.)
- Measures of Neuroleptic Effects on Cognition and Psychomotor Performance in Healthy Volunteers (D. King)
- Index.
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v. 5 ISBN 9780471950400
内容説明
Part of a continuing series of volumes which aims to keep psychopharmacologists acquainted with recent research developments in their field, this work also offers summaries of the topics investigated for those approaching the subject for the first time.
目次
- Measuring the Antecedents and Consequences of Anxiety Neurosis: Methods and Results in Case Registry Studies in the General Population (Sweden)
- Some Methodological Problems of Assessing Severity of Illness and Outcome of Therapeutic Interventions Within Psychopharmacological Drug Research
- Measuring Ethnic Differences in Responses to Psychotropic Drugs
- Psychopharmacological Studies in Demented Elderly
- The Use of Healthy Volunteers in Human Psychopharmacology
- The Psychopharmacology of Attention
- Continuous Long-Term Electrophysical Recording
- Methods, Measures and Meaning
- The Use of Saccadic Eye Movement Measures in Psychopharmacology
- New Indicators of Drug Action
- Measures and Methods in Combining PK-PD Data
- The Actions of Vitamins and Other Nutrients on Psychological Parameters
- Deprenyl, Pergolide, Free Radicals and Neurotropic Factors: New Approaches to Neuroprotection.
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v. 6 ISBN 9780471950417
内容説明
Volume 6 of this invaluable series encompasses the increasing range of issues associated with psychopharmacology, giving up-to-date information not only on the scientific aspects of the subject but also on the social, legal and ethical implications. Chapters include:Stress, glucocorticoids and depression - implications for pharmacological interventionPharmacovigilance and antidepressantsQuality of life in psychopharmacology - what are we measuring and why does it matter - Legal aspects of drugs in the workplaceCognitive testing of new anticonvulsantsHuman Psychopharmacology: Measures and Methods has become established as a standard text in the subject, providing clear and authoritative treatments of the important and current issues in psychopharmacology. This volume will be an invaluable reference point for all those working in the area.
目次
Platelet Intracellular Calcium and the Response to Serotonin as a Peripheral Marker in Mood Disorders (M. Berk). Stress, Glucocorticoids and Depression: Implications for Pharmacological Intervention (T. Dinan). Measuring Cholinergic Function and Cognitive Abilities (W. Riedel, et al.). Assessing Sedating and Alerting Drug Effects: The Multiple Sleep Latency Test (T. Roth & T. Roehrs). Actigraphy in Psychopharmacology (N. Stanley). Cognitive Testing of New Anticonvulsants (M. Trimble). Vascular Dementia: Diagnosis and Management (K. Amar & G. Wilcock). Quality of Life in Psychopharmacology: What are We Measuring and Why Does it Matter? (C. Selai & M. Trimble). Drug Regulation and Psychopharmacology: Measures and Methods (D. Jefferys). Assessing Accident Risk Potential for Psychoactive Drugs (C. Dal Pozzo). Legal Aspects of Drugs in the Workplace (G. Howard). Withdrawal of Psychotropic Drugs from the Market: I: From Thalidomide to Zimeldine (J. Edwards). Withdrawal of Psychotropic Drugs from the Market: II: From Nomifensine to Remoxipride (J. Edwards). Index.
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