Antimutagenesis and anticarcinogenesis mechanisms II

著者

    • International Conference on Mechanisms of Antimutagenesis and Anticarcinogenesis
    • Kuroda, Yukiaki
    • Shankel, Delbert M.
    • Waters, Michael D.

書誌事項

Antimutagenesis and anticarcinogenesis mechanisms II

edited by Yukiaki Kuroda, Delbert M. Shankel, and Michael D. Waters

(Basic life sciences, v. 52)

Plenum Press, c1990

タイトル別名

Antimutagenesis and anticarcinogenesis 2

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注記

"Proceedings of the Second International Conference on Mechanisms of Antimutagenesis and Anticarcinogenesis, held December 4-9, 1988, in Ohito, Japan"--T.p. verso

Includes bibliographical references

内容説明・目次

目次

Antimutagenesis Studies in Japan.- Cancer Prevention: Underlying Principles and Practical Proposals.- Antimutagens in Food.- Anticlastogenic Dietary Factors Assessed in Mammalian Assays.- Antigenotoxic Activity of Carotenoids in Carcinogen-Exposed Populations.- Plant Antimutagens.- Antimutagens and Anticarcinogens in Environmental Toxicology.- Human Biomonitoring in Exposure to Environmental Genotoxicants.- The Concept of Activity Profiles of Antimutagens.- Prevention of Formation of Important Mutagens/Carcinogens in the Human Food Chain.- Free Radicals.- Free Radical Reactions with DNA and its Nucleotides.- Mechanisms of Inactivation of Oxygen Radicals by Dietary Antioxidants and their Models.- Role of Dietary Antioxidants in Protection Against Oxidative Damage.- Antitumor Initiators And Carcinogenesis.- Inhibition of Carcinogenesis by Naturally-occurring and Synthetic Compounds.- Newly Recognized Anticarcinogenic Fatty Acids.- Caloric Restriction in Experimental Carcinogenesis.- Carcinogenicity and Modification of Carcinogenic Response by Antioxidants.- Antitumor Promoters and Carcinogenesis.- Inhibition of Tumor Promotion by DL-?-Difluoromethyl-Ornithine, A Specific Irreversible Inhibitor of Ornithine Decarboxylase.- New Antitumor Promoters: (-)-Epigallocatechin Gallate and Sarcophytols A and B.- Chemoprevention of Mammary Cancer by Retinoids.- Aspects Of Mammalian And Human Genetics.- Suppression of Tumor Promotion by Inhibitors of Poly(ADP)ribose Formation.- Antimutagenic Activity of Vitamins in Cultured Mammalian Cells.- Microcell-Mediated Chromosome Transfer: A Strategy for Studying the Genetics and Molecular Pathology of Human Hereditary Diseases with Abnormal Responses to DNA Damage.- Molecular Aspects Of Mutagenesis And Antimutagenesis.- Genetic Analyses of Cellular Functions Required for UV Mutagenesis in Escherichia coli.- Position of a Single Acetylaminofluorene Adduct within a Mutational Hot Spot is Critical for the Related Mutagenic Event.- Fidelity of Animal Cell DNA Polymerases ? and ? and of a Human DNA Replication Complex.- Molecular Mechanisms of Replicational Fidelity in Escherichia Coli.- Oncogenes And Antioncogenes.- Permanent Conversion of NIH3T3 Cells Transformed by Activated c-Ha-ras, c-Ki-ras, N-ras, OR c-raf, and of Human Pancreatic Adenocarcinoma Containing Activated c-Ki-ras to Apparently Normal Cells by Treatment with the Antibiotic Azatyrosine.- Oncogenes of Stomach Cancers.- Oncogenic Potential and Normal Function of the Proto-oncogenes Encoding Protein-Tyrosine Kinases.- Short Papers.- Inhibition of the Genotoxicity of 3-Amino-1-Methyl-5H- Pyrido[4,3-b]Indole (Trp-P-2) in Drosophila by Chlorophyll.- Inhibition of Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK)-Induced Lung Tumors and DNA Methylation in F344 Rats and A/J Mice by Phenethyl Isothiocyanate.- Proteolytic Activation of UmuD and MucA Proteins for SOS Mutagenesis.- Analysis of Bleomycin-resistant DNA Synthesis in Cells from an Inherited Human Disorder, Ataxia Telangiectasia.- Tumor Dose-response Studies with Aflatoxin B1 and the Ambivalent Modulator Indole-3-carbinol: Inhibitory versus Promotional Potency.- Antimutagenesis in Yeast by Sodium Chloride, Potassium Chloride, and Sodium Saccharin.- The Use of Drosophila as an in VIVO System to Study Modifiers of Chemical Mutagenesis.- The Mouse Mutant, "Wasted": Tissue-specific Radiation Sensitivity and Hematopoietic Cell Lineages.- Antimutagenic Effects of Tumor Promoters-Co-mutagenic Effects of Co-carcinogens.- Antimutagenic Effects of Dimethyl Sulfoxide on Metabolism and Genotoxicity of Benzene in Vivo.- Possible Antitumor Promoter in the Glandular Stomach: Calcium Chloride.- Reversion of Transformed NIH 3T3 Cells to Flat Cells by Inhibitors of Poly(ADP-ribose) Polymerase.- Inactivation of Mutagenic Heterocyclic and Aryl Amines by Linoleic Acid 13-Monohydroperoxide and Methemoglobin.- Establishment of a Highly Reproducible Transformation Assay of a Ras-Transfected Balb 3T3 Clone by Treatment with Promoters.- Antimutagenic Effect of umuD Mutant Plasmids: Isolation and Characterization of umuD Mutants reduced in their Ability to Promote UV Mutagenesis in Escherichia Coli.- Antitumor-promoting Activity of Sesquiterpene Isolated from an Herbal Spice.- Inhibitory Effects of Chlorogenic Acid, Reserpine, Polyprenoic ACID (E-5166), or Coffee on Hepatocarcinogenesis in Rats and Hamsters.- Antimutagenic Structure Modification of Quinoline: Fluorine-substitution at Position-3.- Mutagenicity and Antimutagenicity of Thai Medicinal Plants.- Influence of Potential Antioxidants on Free-radical Damage of Lymphocytes.- Specificity of Antimutagens Against Chemical Mutagens in Microbial Systems.- Classification of Mechanisms of Inhibitors of Mutagenesis and Carcinogenesis.- Antimutagenic Effects of Chlorophyllin.- Participants, Speakers, and Chairmen.

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