Immunogenicity : proceedings of a UCLA Symposium held at Steamboat Springs, Colorado, January 21-28, 1989

著者

書誌事項

Immunogenicity : proceedings of a UCLA Symposium held at Steamboat Springs, Colorado, January 21-28, 1989

editors, Charles A. Janeway, Jr., Jonathan Sprent, Eli Sercarz

（UCLA symposia on molecular and cellular biology, new ser., v. 113）

Wiley-Liss, c1990

大学図書館所蔵 件 / 全6件

この図書・雑誌をさがす

注記

Includes bibliographical references

内容説明・目次

内容説明

A clear understanding of immunogenicity is necessary for the design of effective vaccines and the avoidance of unnatural immune responses. This study offers a thorough examination of the involved mechanisms of immunogenicity and its practical applications. It focuses on the events that lead to T-cell activation and memory generation, deals with the processing and presentation of antigens to T-cells, examines recognitive and signalling events and covers the processes surrounding lymphocyte activation. There is a full discussion of immunological memory and the role of immunogenicity in infectious diseases, vaccine design, transplantation immunity and autoimmunity.

目次

  • Partial table of contents:
  • ANTIGEN UPTAKE AND PROCESSING
  • Where Do Antigens Associate with MHC Class I Molecules?
  • (J. Yewdell, et al.)
  • THE GENERATION OF AN IMMUNOGENIC LIGAND
  • Effects of Peptide Competition on Antigen Presentation (L. Adorini, et al.)
  • T CELL RECOGNITION OF ANTIGEN: MHC COMPLEXES
  • The Role of CD4 in T Cell Activation (S. Goldman, et al.)
  • TRANSMEMBRANE SIGNALING IN LYMPHOCYTES
  • Regulation of Cytoplasmic Calcium Concentration in T Cells (J. Ledbetter, et al.)
  • THE ROLE OF THE ANTIGEN PRESENTING CELL IN IMMUNOGENICITY
  • Dendritic Cells: Nature's Adjuvant (R. Steinman, et al.)
  • TOLERANCE: THE INACTIVATION OF LYMPHOCYTES BY SPECIFIC LIGAND
  • Transgenic Model for Tissue Specific Antigens: Tolerance and Clonal Anergy (D. Lo, et al.)
  • THE GENERATION AND PERSISTENCE OF IMMUNOLOGICAL MEMORY
  • Immunological Memory: Longlived Cells or Longlived Antigen?
  • (D. Gray)
  • IMMUNOGENICITY IN DISEASE
  • Workshop on Immunogenicity in Infectious Diseases (P. Doherty & S. Kaufmann)
  • SYSTEMS QUESTIONS IN IMMUNOGENICITY
  • Distinct Antigen Presenting Cells for Activation of Suppressor and Contrasuppressor T Cells (H. Braley-Mullen)
  • Index.

「Nielsen BookData」 より

関連文献： 1件中  1-1を表示

詳細情報

ページトップへ