Vaccines for sexually transmitted diseases

著者

書誌事項

Vaccines for sexually transmitted diseases

edited by A. Meheus, R.E. Spier

Butterworths, 1989

統一タイトル

Vaccine

大学図書館所蔵 件 / 全5件

この図書・雑誌をさがす

注記

"Proceedings of the conference 'Vaccines for sexually transmitted diseases,' Oxford, UK, 5-7 April 1989, sponsored by the journal Vaccine, co-sponsored by the World Health Organization."

Includes bibliographical references

内容説明・目次

内容説明

One of the most disappointing aspects of medicine during the past 25 years has been the great increase in the incidence of infections due to sexually transmitted agents. This work aims to take stock of our actual knowledge on STD vaccine development and to outline directions for future research. The book identifies a need to make progress both in changing peoples sexual behaviour as well as providing safe and effective vaccine protection against STDs.

目次

  • Part 1 Introduction: epidemiology
  • immunological principles of vaccine design
  • selection and suitability of adjuvants. Part 2 Gonorrhoea and candidiasis: problems and prospects for the development of a vaccine against gonorrhoea
  • serum and vaginal fluid antibodies against the gonococcal major iron-regulated protein in women with pelvic inflamatory disease or uncomplicated infection
  • D.651, an oral vaccine for the prevention of vulvovaginal candidiasis
  • preparation and characterization of pilin synthetic peptide-MIRP conjugates as a potential vaccine for the prevention of gonococcal infections
  • specificity of serum immunoglobulin G subclass response to gonorrhoea in women
  • molecular biology of gonococcal porim protein P.I. Part 3 Chlamydia: immunity to chlamydial infections
  • prevention of pulmonary and genital chlamydia infection by oral immunization
  • stability and safety of a chlamydial live vaccine against enzootic abortion of ewes
  • passive transfer experiments to study the protection against "chlamydia psittaci" infection of the mouse
  • lymphocyte proliferation response to chlamydial antigens in human ocular chlamydial infections
  • production and immunoanalysis of recombinant "E. Trachomatis" serovar D major outer membrane protein (MOMP). Part 4: Syphilis
  • experimental syphilis vaccines - use of aroA salmonella typhimurium to deliver recombinant "treponema pallidum" antigens
  • cellular and molecular approaches to the development of a vaccine for syphilis. Part 5 Hepatitis B: current and future hepatitis B vaccines
  • development and clinical studies with a recombinant DNA hepatitis B vaccine
  • ISCOMs (immune-stimulating complexes) and the presentation of HBsAg peptides. Part 6 Papillomaviruses: a vaccine to genital papillomaviruses - is it feasible?
  • vaccination against polyoma - and papillomavirus-induced tumours using vaccinia recombinants expressing non-structural proteins. Part 7 Herpes simplex: Herpes simplex vaccines
  • development of an HSV subunit vaccine
  • poor immunogenicity as the reasons for the ineffectiveness of a glycoprotein subunit vaccine for genital herpes
  • efficacy of yeast-derived glycoprotein B of herpes simplex virus on the development of herpetic lesion after intravaginal challenge with HSV type 2
  • follow-up report on 101 subjects vaccinated with Skinner herpes vaccine
  • the development of a subunit cytomegalovirus vaccine
  • effect of HSV-1 antigen preparations derived using a Zwitterionic detergent on HSV-1 latency using a mouse model
  • characterization of an HSV-1 subunit vaccine and its enhanced immunogenicity in the form of an immunostimulating comples (HSV-1 ISCOM) preparation
  • (Part contents)

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