Pharmacology of adrenoceptors

著者

書誌事項

Pharmacology of adrenoceptors

edited by E. Szabadi, C.M. Bradshaw, and S.R. Nahorski

VCH Verlagesellschaft , VCH Publishers, c1985

  • :gw
  • :U. S.

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注記

Proceedings of a satellite symposium of the IUPHAR 9th International Congress of Pharmacology

Includes bibliographies and index

内容説明・目次

内容説明

This collection of twenty-seven papers reflects the current state of adrenoceptor pharmacology and many of the remarkable new developments that have occurred recently in the field. The papers were presented at the University of Manchester in 1984 before a satellite symposium of the Ninth International Congress of Pharmacolgy. The book covers the major areas of adrenoceptor pharmacology - classification, biochemistry, cellular electrophysiology, release modulation, and clinical aspects - and also discusses the distribution of various types of adrenoceptors in the central nervous system, as well as the pattern of regional differences between brain structures. Forty-three contributed papers are included as poster communications.

目次

  • Part I/Classification of Adrenoceptors: Molecular and Pharmacological Approaches
  • Selective a1-Adrenoceptor Agonists and Antogonists
  • Selective a2-Adrenoceptor Agonists and Antogonists
  • The Characterization of Mammalian b1- and b2-Adrenergic Receptors
  • Biochemical and Pharmacological Approaches to b-Adrenoceptor Subclassification
  • The Heterogeneity of Adrenergic Receptors: Chairman's Comments
  • Part II/Biochemical Consequences of Adrenoceptor Activation
  • The Human Platelet a2-Adrenergic System: The Role of Na+ in Epinephrine-Receptor Interactions, Arachidonic Acid Release and CA++ Mobilization
  • a1-Adrenoceptor Activation of Phosphoinositide Breakdown and Elevation of Intracellular Ca2
  • Regulation of b-Adrenergic Receptors
  • Biochemical Consequences of Adrenoceptor Activation: Chairman's Comments
  • Part III/Electrophysiological Consequences of Adrenoceptor Activation: Nerve and Glia Cells
  • Pharmacology of Hippocampal Adrenoceptors in 'in vitro' Brain Slice Preparations
  • The Pharmacology of the Neuronal a-Adrenoceptor the Cerebral Cortex
  • Adrenoceptors on Glial Cells
  • Electrophysiological Consequences of Adrenoceptor Activation: Nerve and Glia Cells. Chairman's Comments
  • Part IV:Electrophysical Consequences of Adrenoceptor Activation: Smooth Muscle and Gland Cells
  • Electrophysiological Differentiation of Subtypes of a-Adrenoceptors in the Canine Saphenous Vein
  • Adrenoceptors and the Ionic Permeability of Liver Cells
  • Adrenoceptors in Liver and Smooth Muscle Cells: Chairman's Comments
  • Part V/Modulation of Transmitter Release by Adrenoceptors
  • Site of Action of Presynaptic Inhibition Mediated via Adrenoceptors
  • Modulation of Cholinergic Transmission by Adrenoceptors
  • Modulation of Noradrenaline Release by Presynaptic Adrenoceptors in Experimental Hypertension
  • a-Adrenoceptors, Presynaptic Modulation: Facts and Hypothesis. Chairman's Comments
  • Part VI/Clinical Significance of Adrenoceptors
  • Adrenoceptors and Hypertension
  • Adrenoceptors in Bronchial Asthma
  • Adrenergic Receptors on Human Blood Cells
  • Adrenoceptors and Abnormal Platelet Function
  • Adrenoceptors and Depression
  • Clinical Significance of Adrenoceptors: Chairman's Comments
  • The Nature of Adipocyte b-Adrenoceptor(s)
  • Part VII/Poster Communications.

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