Formulation factors in adverse reactions
著者
書誌事項
Formulation factors in adverse reactions
(Topics in pharmacy, v. 1)
Wright, 1990
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注記
Includes bibliographies and index
内容説明・目次
内容説明
This book, dealing with adverse reactions in a pharmaceutical context, has five contributors who look at adverse reactions to parenterals and excipients in pharmaceutical formulations as well as the effects of the transit of oral dosage forms, physical properties of formulations and drug allergy.
目次
- Part 1 Adverse reactions to excipients in pharmaceutical formulations, P.F.D'Arcy: excipients are not inactive
- spectrum and incidence of excipient reactions
- colouring agents
- preservatives
- sugars, sweeteners and flavours
- components of ointments, creams and other topical formulations
- alcohols
- problems and possible solutions. Part 2 Drug allergy - chemical and pharmaceutical aspects, H.Bundgaard: immunochemical mechanisms of drug allergy
- routes of formation of antigens from drugs. Part 3 Adverse reactions to parenterals, M.C.Allwood: excipients
- particulates as a case of adverse reactions to parenterals
- administration of parenterals. Part 4 Adverse reactions to the transit of oral dosage forms, K.S. Channer: drug-induced oesophageal ulceration
- factors influencing oesophageal transit
- drug absorption after delayed oesophageal transit. Part 5 Physical properties of formulations and adverse reactions to medicines, A.T.Florence and E.G.Salole: ocular medication
- oral dosage forms
- parenteral therapy
- aerosols.
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