Controlled release of biologically active agents
著者
書誌事項
Controlled release of biologically active agents
（Advances in experimental medicine and biology, v. 47）
Plenum Press, [1974]
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注記
Proceedings of a symposium held in Birmingham, Ala., Apr. 19-20, 1973, sponsored by the Southern Research Institute
Includes bibliographical references
内容説明・目次
内容説明
The Symposium on Controlled Release of Biologically Active Agents was held under sponsorship of Southern Research Institute in Birmingham, Alabama, April 19 and 20, 1973. The announced purpose of the symposium was to encourage an exchange of information among the ex- perts working in various fields of controlled release and the scientists and technologists interested in applying the concepts. The number of registrants (over 120), the diverse nature of the organizations represented, and the enthusiastic participation of attendees in the discussions testified to intense and broad interests in controlled release. The papers pre- sented at the symposium should serve well to introduce the principles of controlled release and demonstrate a few of the promising applications. Controlled release is an important step toward im- proving the delivery of a biologically active agent to its target. Precise administration of an agent can substantially reduce the concentration required for beneficial effects and thus minimize deleterious effects to the organism or to the environment.
Through con- trolled release, older agents whose efficacies are established may prove more reliable, and newer agents whose high potencies or low stabilities have inhibited use may prove more suitable. Controlled release there- fore offers both an alternative and a complementary route to the increasingly costly and demanding search for agents of greater specificity.
目次
to Controlled Release.- Controlled Release: Mechanisms and Rates.- Influence of Physico-Chemical Properties of Drug and System on Release of Drugs from Inert Matrices.- Silicone Rubber: A Drug-Delivery System for Contraceptive Steroids.- Factors Affecting the Release of Steroids from Silicones.- Development of a Delivery System for Prostaglandins.- Cervical Hydrogel Dilator: A New Delivery System for Prostaglandins.- Long-Acting Delivery Systems for Narcotic Antagonists.- Controlled-Release Pesticides: Concepts and Realization.- Author Index.
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