The Biology and chemistry of polyamines : proceedings of an Argentine-Japanese joint seminar, Buenos Aires, Argentina, April 9-12, 1989

書誌事項

The Biology and chemistry of polyamines : proceedings of an Argentine-Japanese joint seminar, Buenos Aires, Argentina, April 9-12, 1989

edited by Sara M. Goldemberg and Israel D. Algranati ; technical editor, Karen M. Williams

(ICSU Press symposium series, no. 12)(I.U.B. symposium series, v. 184)

Published for the ICSU Press by IRL Press, c1990

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注記

Papers presented at the International Symposium on the Biology and Chemistry of Polyamines

Includes bibliographical references

内容説明・目次

内容説明

The multifarious role of polyamines in controlling metabolic processes is well known and documented, as shown by the increase in the literature in the last decade. Specialized international meetings take place in several parts of the world to report and discuss progress in different studies on polyamines. This volume derives from an Argentine-Japanese Joint Seminar, held in Buenos Aires in April 1989, with the participation of scientists from Argentina, Japan, United States, Finland, Sweden, Israel, Italy and England. The contributions presented here show the current focus of research in aspects of the biology and chemistry of polyamines, and thus enable further progress in the understanding of the multiple roles of these polycations to be made. Topics for presentation included the involvement of polyamines in metabolic regulation, mammolian cell growth and differentiation, the role of polyamines in micro-organisms and viruses and the design of polyamine analogues. Polyamines play a vital role in normal cellular development and disease and the work presented here will be of interest to researchers in molecular biology, pharmacology, microbiology and oncology.

目次

  • Biochemical functions of unusual polyamines found in the cells of extreme thermophiles, T.Oshimo et al
  • responsibility of ribosomal protein SI for the activation of ribosomes by polyamines, K.Igarashi et al
  • a possible involvement of polyamines in the regulation of transmembrane signalling events, C.M.Caldarara et al
  • human ornithine decarboxylase gene - properties and expression in hamster cells, J.Janne et al
  • regulation of the activity and expression of ornothine decarboxylase in lymphocytes, S.Otani et al
  • feedback regulation of polyamine synthesis in mammilian cells, L.Persson et al
  • structual modifications in ODC protein affecting its activity, stability and antizyme binding, J.L.A.Mitchell et al
  • modulation of ornithine decarboxylase and polyamine pools by alkylputrescines, R.B.Frydman et al
  • distribution and properties of ornithine decarboxylase antizyme, S.Matsufuji et al
  • cloning and primary structure of human spermidine synthase, T.O.Eloranta et al
  • inhibitors acting as putrescine or spermidine binding site of aminopropyltransferases, A.Shirahata and K.Samejima
  • functions of polyamines in "escherichia coli", E.S.Canellakis et al
  • structural alterations in polyamine-depleted "saccharomyces cerevisiae", S.H.Goldemberg et al
  • polyamines and the growth of pathogenic viruses, A.S.Tyms et al
  • polyamines in "trypanosoma cruzi" and "leishmania Mexicana", I.D.Algranati et al
  • a role for polyamines in differentiation and growth of plant roots, A.Altman et al
  • novel polyamines and guanidinoamines in higher plants, S.Matsuzaki et al
  • transport and metabolism of polyamines in primary cell cultures, M.A.Grillo et al
  • polyamines and oncogenes, U.Bachrach et al
  • ornithine decarboxylase gene expression in normal and transformed cells, E.Holtta and L.Sistonen
  • polyamines and angiogenesis - inhibition of tumor angiogenesis by the irreversible inhibitor of ornithine decarboxylase, a-diflouromethylornithine, M.Takigawa et al
  • inhibitors of polyamine biosynthesis as antimetastatic agents, P.S.Sunkara
  • cure of mouse leukemia by polamine depletion, O.Heby et al
  • strategies in the synthesis of alkylated putrescines, B.Frydman et al.

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