Large-scale mammalian cell culture technology
著者
書誌事項
Large-scale mammalian cell culture technology
(Bioprocess technology, v. 10)
Dekker, c1990
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注記
Includes bibliographical references
Includes index
内容説明・目次
内容説明
An interdisciplinary approach, integrating biochemistry, biology, genetics, and engineering for the effective production of protein pharmaceuticals. The volume offers a biological perspective of large-scale animal cell culture and examines diverse processing strategies, process management, regulator
目次
Series Introduction, Series Introduction, Contributors, 1: Large-Scale Mammalian Cell Culture: A Perspective, 2: Use of Recombinant DNA Technology for Engineering Mammalian Cells to Produce Proteins, 3: Large-Scale Animal Cell Culture: A Biological Perspective, 4: Mammalian Cell Physiology, 5: Cell Banking, 6: Expression of Cloned Proteins in Mammalian Cells: Regulation of Cell-Associated Parameters, 7: Assay Requirements for Cell Culture Process Development, 8: Nonperfused Attachment Systems for Cell Cultivation, 9: Perfusion Systems for Cell Cultivation, 10: Suspension Culture of Mammalian Cells, 11: Microcarrier Culture Systems, 12: Microencapsulation of Mammalian Cells, 13: Continuous Culture with Macroporous Matrix, Fluidized Bed Systems, 14: Downstream Processing of Proteins from Mammalian Cells, 15: Management of Process Technology, 16: Monitoring and Control of Animal Cell Bioreactors: Biochemical Engineering Considerations, 17: Methods for the Detection of Adventitious Viruses in Cell Cultures Used in the Production of Biotechnology Products, 18: Continuous Cell Substrate Considerations, 19: Process Validation for Cell Culture-Derived Pharmaceutical Proteins, 20: Quality Control of rDNA-Derived Human Tissue-Type Plasminogen Activator, 21: Design and Construction of Manufacturing Facilities for Mammalian Cell-Derived Pharmaceuticals, 22: Large-Scale Propagation of Insect Cells, Index
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