Antiviral chemotherapy : new directions for clinical application and research : proceedings of the conference New Directions in Antiviral Chemotherapy held in San Francisco, November 4-6, 1985
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書誌事項
Antiviral chemotherapy : new directions for clinical application and research : proceedings of the conference New Directions in Antiviral Chemotherapy held in San Francisco, November 4-6, 1985
Elsevier, c1986
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注記
Includes bibliographies and index
内容説明・目次
内容説明
The excitement surrounding research in antiviral chemotherapy is comparable to that generated by the discovery of penicillin in the 1940s. Antiviral Chemotherapy: New Directions for Clinical Application and Research presents the latest findings on several important topics including interferon, amantadine (used in influenza prophylaxis), and current controversies in clinical management. Providing a comprehensive, up-to-date and in-depth review of the subject, this book examines antiviral chemotherapy from the standpoint of individual drugs (mechanism of action, spectrum, pharmacology, clinical efficacy) as well as from the perspective of the clinician managing specific antiviral infections (appropriate diagnostic tests, indications for antiviral therapy, and selection from among available chemotherapeutic agents). This information will be of use to scientists and physicians with a special interest in infectious diseases. This volume contains the edited proceedings of the conference on antiviral chemotherapy held in San Francisco, November 4-6, 1985.
目次
Preface. Contributors. Landmark Achievements in Antiviral Chemotherapy. Interferon: A Decade of Accomplishments: Foundations of the Future. The Uwse of Interferons for Treatment of Herpes Virus Infections. Use of Interferons for Prevention and Treatment of Respiratory Viral Infections. Effect of Interferon on Reactivation of Oral Herpes Simplex Infection After Microvascular Decompression for Trigeminal Neuralgia. Effect of Interferon on Primary Genital Herpes. Use of Interferons for Papillomavirus Infections. The Antiviral Spectrum and Mechanism of Action of Amantadine and Rimantadine. Clinical Efficacy, Pharmacology, and Toxicity of Amantadine and Derivatives. Overview of Ribavirin, Selenazole and Derivatives. The Mechanism of Action of Ribavirin. Management of Respiratory Viral Infections: Influenza. Chemotherapy of Respiratory Syncytial Virus Infections. Discussion Following the Respiratory Syncytial Virus Symposium. Win 51711 - A Novel Drug for the Treatment of Enterovirus Infections. Immunotherapy of Enterovirus Infections. Prospects for Chemotherapy of Retroviruses. History, Mechanism of Action, Spectrum and Selectivity of Nucleoside Analogs. Comparative Pharmacology of Nucleoside Analogs with Antiviral Activity. Therapeutic Approaches to Herpes Simplex Encephalitis and Neonatal Herpes Simplex Virus Infections. Acyclovir for the Treatment of Oral, Facial, and Genital Herpes Simplex Virus Infection. Acyclovir for Varicella-Zoster Virus Infections. Nucleoside Analogs for Epstein-Barr Virus Infections. Therapy for Ocular Herpes Simplex Virus Infections. 9-(1, 3-Dihydroxy-2-Propoxymethyl) Guanine (DHPG) for Treatment of Cytomegalovirus Infections. The Toxicity of Nucleoside Analogs. Resistance of Herpes Viruses to Nucleoside Analogues - Mechanisms and Clinical Importance.
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