Pathophysiology of the blood-brain barrier
著者
書誌事項
Pathophysiology of the blood-brain barrier
(Fernström Foundation series, v. 14)
Elsevier , Sole distributors for the USA and Canada, Elsevier Science Pub. Co., 1990
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内容説明・目次
内容説明
The blood-brain barrier, a concept including all morphological and functional mechanisms that restricts or facilitates the passage of substances from blood to brain, enables the brain environment to be regulated relatively independently from concentration and fluctuations in plasma constituents. The various aspects on the blood-brain barrier have been extensively discussed in a number of recent symposia and our knowledge on the blood-brain barrier physiology has advanced impressively during the last decade. However, as to the pathophysiology and the long-term consequences of a transient or permanent barrier damage, little is known - a fact attributable to the limited amount of interest shown in this area of research until recently. The idea to arrange a Fernstrom symposium on the consequences of barrier damage emerged in 1987, when findings in Barbro Johansson's Laboratory of Experimental Neurology indicated that opening of the blood-brain barrier in various experimental models could lead to permanent neuronal injury.
目次
Content Headings: List of Participants. Preface. The Erik K. Fernstrom Foundation. Acknowledgements. Section I. Current Concepts of the Blood-Brain Barrier (papers 1-8). Section II. Pathophysiology of Barrier Mechanisms (papers 9-16). Section III. Therapeutic Role of Barrier Modifications (papers 17-22). Section IV. Blood-Brain Barrier in Neurotoxicology (papers 23-27). Section V. The Blood-Brain Barrier in the Pathophysiology of Cerebrovascular Lesions (papers 28-34). Section VI . Afferent and Efferent Pathways from the Brain to the Immune System (papers 35-41). Section VII . Antigen Presentation in the Central Nervous System (papers 42-44). Section VIII . Immunocytotherapy in the Brain (papers 45-47). Section IX . Transplantation in the Central Nervous System (papers 48-53). Full contents list available on request from the Publisher. Imprint Amsterdam
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