Annual reports in medicinal chemistry
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Annual reports in medicinal chemistry
Academic, 1965-
- 1965
- 1966
- 1967
- 1968
- 1969
- 1970
- v. 4
- v. 5
- v. 6
- v. 7
- v. 8
- v. 9
- v. 10
- v. 11
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- v. 13
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- v. 15
- v. 16
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- v. 19
- v. 20
- v. 21
- v. 22
- v. 23
- v. 24
- v. 25
- v. 26
- v. 27
- v. 28
- v. 29
- v. 30
- v. 31
- v. 32
- v. 33
- v. 34
- v. 35
- v. 36
- v. 37
- v. 38
- v. 39
- v. 40
- v. 41
- v. 42
- v. 43
- v. 44
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Available at / 32 libraries
-
Kyoto Pharmaceutical University Library
v. 22499.2||A.6||22002369I,
v. 23499.2||A.6||23002370B, v. 24499.2||A.6||24002371A, v. 25499.2||A.6||25002372I, v. 26499.2||A.6||26002373G, v. 27499.2||A.6||27047713D, v. 28499.2||A.6||28080534D, v. 29499.2||A.6||29082852B, v. 30499.2||A.6||30086351D, v. 31499.2||A.6||31090828C, v. 32499.2||A.6||32094498A, v. 33499.2||A.6||33097872I, v. 34499.2||A.6||34101216J, v. 35499.2||A.6||35085903G, v. 36499.2||A.6||36105566G, v. 37499.2||A.6||37108107B, v. 38499.2||A.6||38110375A, v. 39499.2||A.6||39113075H, v. 40499.2||A.6||40115934I, v. 41499.2||A.6||41118711C, v. 42499.2||A.6||42121669E, v. 43499.2||A.6||43124326I, v. 44499.2||A.6||44126700B, v. 45499.2||A.6||45129258H, v. 46499.2||A.6||46131877C -
1965491.405||ANN220801410,
1966491.405||ANN220801428, 1967491.405||ANN220801436, 1968491.405||ANN220801444, 1969491.405||ANN220801452, 1970491.405||ANN220801461, v. 7491.405||ANN220801479, v. 8491.405||ANN220801487, v. 9491.405||ANN220801495, v. 10491.405||ANN220801509, v. 11491.405||ANN220801517, v. 12491.405||ANN220801525, v. 13491.405||ANN220801533, v. 15491.405||ANN220801541, v. 16491.405||ANN220801550, v. 17491.405||ANN220801568, v. 18491.405||ANN220801576, v. 19491.405||ANN220801584, v. 20491.405||ANN220801592, v. 21491.405||ANN220801606, v. 22491.405||ANN220801614, v. 23491.405||ANN220834954, v. 24491.405||ANN220834962, v. 25491.405||ANN220852618, v. 26491.405||ANN220877271, v. 27491.405||ANN220896780, v. 28491.405||ANN220919364, v. 29491.405||ANN220931356, v. 30491.405||ANN220944997, v. 31491.405||ANN220958050, v. 32491.405||Ann220981345, v. 33491.405||Ann221008519, v. 34491.405||Ann221033025, v. 35491.405||Ann221052097 -
v. 13190||ANN-1||13B8300091,
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19650080123529,
19662016101690, 19672016101703, 19680080123530, 19692016053556, 19702016101725, v. 72016101736, v. 82016101747, v. 90080134577, v. 102016101758, v. 112016101769, v. 122016101770, v. 132016101781, v. 150081077865, v. 160090104468, v. 170090104479, v. 180090104480, v. 190090104491, v. 200090104505, v. 270092099205, v. 280093075722, v. 290094053409, v. 300095044308, v. 310096018284, v. 320097014351, v. 330098043859, v. 340099047515, v. 355200045499, v. 365200146812, v. 375200251467, v. 385200347154, v. 395200462155, v. 405200574445, v. 415200655432, v. 425200770591, v. 435200851269, v. 445200951976, v. 455201053414, v. 465201158535, v. 475201246110, v. 485201350129, v. 495201447932, v. 505201816791, v. 515201848447, v. 525201933975, v. 535201938572 -
Medical Library, The University of Tokyo図書
v. 35ZA:AD4310732500,
v. 36ZA:AD4310779667, v. 37ZA:AD4310848470, v. 38ZA:AD4310898020, v. 39ZA:AD4310942927, v. 40ZA:AD4310991700, v. 41ZA:AD4311034948, v. 42ZA:AD4311086328, v. 43ZA:AD4311129011, v. 44ZA:AD4311183547, v. 45ZA:AD4311226296, v. 46ZA:AD4311265807, v. 47ZA:AD4311296448, v. 48ZA:AD4311329215, v. 49ZA:AD4311355855 -
Graduate School of Pharmaceutical Sciences, Pharmaceutical Sciences Library, University of Tokyo図書
1967491.4:A49:19675800068818,
1968491.4:A49:19685800068826, 1970491.4:A49:19705800068834, v. 7491.4:A49:75800068842, v. 8491.4:A49:85800068859, v. 9491.4:A49:95800068867, v. 10491.4:A49:105800068875, v. 11491.4:A49:115800068883, v. 12491.4:A49:125800023557, v. 13491.4:A49:135800023565, v. 14491.4:A49:145800023573, v. 15491.4:A49:155800023581, v. 16491.4:A49:165800023599, v. 17491.4:A49:175800023607, v. 18491.4:A49:185800023615, v. 19491.4:A49:195800023623, v. 20491.4:A49:205800023631, v. 21491.4:A49:215800023649, v. 22491.4:A49:225800023656, v. 23491.4:A49:235810152750, v. 24491.4:A49:245810156074, v. 25491.4:A49:255810163229, v. 26491.4:A49:265810168616, v. 27491.4:A49:275810176817, v. 28491.4:A49:285810183912, v. 29491.4:A49:295810189737, v. 30491.4:A49:305810196450, v. 31491.4:A49:315810202472, v. 32491.4:A49:325810217447, v. 33491.4:A49:335810223668, v. 34491.4:A49:345810231612, v. 35491.4:A49:355810238435, v. 36491.4:A49:365810246222, v. 37491.4:A49:375810256429, v. 38491.4:A49:385810266162, v. 39491.4:A49:395810276633, v. 40491.4:A49:405810287697, v. 41491.4:A49:415810291236, v. 42491.4:A49:425810300813, v. 43491.4:A49:435810305515, v. 44491.4:A49:445810312909, v. 45491.4:A49:455810322809, v. 46491.4:A49:465810333426, v. 47491.4:A49:475810349182, v. 48491.4:A49:485810360122, v. 49491.4:A49:495810368349 -
Tokyo University of Agriculture and Technology Library, Fuchu Library
v. 45499.3/AD45/遠藤文庫10812591,
v. 47499.3/AD47/遠藤文庫10813263 -
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1965491.4||A49||1001761,
1966491.4||A49||2001762, 1967491.4||A49||3001763, 1968491.4||A49||4001764, 1969491.4||A49||5001765, 1970491.4||A49||6001766, v. 7491.4||A49||7001767, v. 8491.4||A49||8001768, v. 9491.4||A49||9001769, v. 10491.4||A49||10001770, v. 11491.4||A49||11001771, v. 12491.4||A49||12001772, v. 15491.4||A49||15001535 -
v. 40491.5/A49-1/402000000027207,
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1965499.2||A128108614,
1966499.2||A128301881, 1967499.2||A128108615, 1968499.2||A||4128108616, 1969499.2||A||5128108617, 1970499.2||A||6128108618, v. 7499.2||A128108619, v. 8499.2||A128108620, v. 9499.2||A128108621, v. 10499.2||A128108622, v. 11499.2||A128108623, v. 12499.2||A128108624, v. 13499.2||A128108625, v. 14499.2||A128108626, v. 15128402312, v. 16128400701, v. 17128400702, v. 18499.2||A||18128400703, v. 19128600246, v. 20128700310, v. 21128700311, v. 22128900272, v. 23129100549, v. 24129100548, v. 25499.2||A||25129601008, v. 26499.2||A||26129200563, v. 27499.2||A||27129300344, v. 28499.2||A129400287, v. 29499.2||A||29129601009, v. 30499.2||A||30129601010, v. 31499.2||A||31129700217, v. 32499.2||A||32141500016, v. 33499.2||A129900395, v. 34499.2||A129900700, v. 35499.2||A||35141500017, v. 36499.2||A||36120100351, v. 37499.2||A||37120200364, v. 38499.2||A||38120300293, v. 39499.2||A||39120400272, v. 40499.2||A||40120500252, v. 41499.2||A||41120600226, v. 42499.2||A||42120700129 -
1965P.2/A49/19650000033635,
1966P.2/A49/19660000033636, 1967P.2/A49/19670000033638, 1968P.2/|A49/19680000033639, 1969P.2/A49/19690000033640, 1970P.2/A49/19700000033641, v. 7P.2/A49/70000033642, v. 8P.2/A49/80000033643, v. 9P.2/A49/90000033644, v. 10P.2/A49/100000033645, v. 11P.2/A49/110000033646, v. 12P.2/A49/120000033647, v. 13P.2/A49/130000033648, v. 14P.2/A49/140000033649, v. 15P.2/A49/150000033650, v. 16P.2/A49/160000033651, v. 17P.2/A49/170000033652, v. 18P.2/A49/180000033653, v. 19P.2/A49/190000033654, v. 20P.2/A49/200000033655, v. 21P.2/A49/210000033656, v.22P.2/A49/220000033657, v.23P.2/A49/230000033658, v.24P.2/A49/240000033659, v.25P.2/A49/250000033660, v.26P.2/A49/260000033661, v.27P.2/A49/270000033662, v.28P.2/A49/280000033663, v.29P.2/A49/290000033664, v.30P.2/A49/300000033665, v.31P.2/A49/310000033666, v.32P.2/A49/320000033667, v.33P.2/A49/330000033668, v.34P.2/A49/340000036233, v.35P.2/A49/352000040297, v.36P.2/A49/362000041447, v.37P.2/A49/372000042581, v.38P.2/A49/382000044962, v.39P.2/A49/392000046173, v. 40P.2/A49/402000048429, v. 41P.2/A49/412000048466 -
v. 10491.4||A49||1011032544,
v. 11491.4||A49||1111032545, v. 12491.4||A49||1211032546, v. 13491.4||A49||1311032547, v. 14491.4||A49||1411032548, v. 15491.4||A49||1511032549, v. 16491.4||A49||1611032550, v. 17491.4||A49||1711032551, v. 18491.4||A49||1811032552, v. 19491.4||A49||1911032553, v. 20491.4||A49||2011032554, v. 21491.4||A49||2111032555 -
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v.34-: editor-in-chief: Annette M. Doherty
v.41: editor-in-chief: Anthony Wood
v.42-: editor-in-chief: John E. Macor
v.47-: editor-in-chief: Manoj C. Desai
v.50, 52, 53: editor-in-chief: Stephen Neidle
v.51: editor-in-chief: Maurizio Botta
Description and Table of Contents
- Volume
-
v. 21 ISBN 9780120405213
Description
- Volume
-
v. 25 ISBN 9780120405251
Description
Table of Contents
- CNS agents, J.M.McCall
- cardiovascular and pulmonary agents, D.W.Robertson
- chemotherapeutic agents, J.J.Plattner
- metabolic diseases and endocrine function, W.F.Johns
- topics in biology, K.B.Seamon
- topics in chemistry and drug design, F.J.Vinick
- trends and perspectives, J.A. Bristol.
- Volume
-
v. 26 ISBN 9780120405268
Description
Table of Contents
- CNS agents, J.M. McCall
- new anxiolytics, L.J. Browne and K.J. Shaw
- recent advances in excitatory amino acid research, G.Johnson and C.F. Bigge
- progress in anti-depressant drugs, D.W. Robertson and R.W. Fuller
- diversity of neuronal calcium channels, N.A. Saccomano and A.H. Ganong
- recent advances in neurokinin receptor anatagonists, M.E. Logan, et al
- antipsychotics, L.D. Wise and T.G. Heffner
- cardiovascular and pulmonary agents, D.W. Robertson
- angiotensin/renin modulators, W.J. Greenlee and P.K.S. Siegl
- potassium channel activators, J.M. Evans and S.D. Longman
- endogenous vasoactive peptides, A.M. Doherty
- emerging drug discovery targets in thrombosis and coagulation, R.J. Shebuski
- serotonin modulators and cardiovascular/gastrointestinal disease, J.E. Audia and M.L. Cohen
- pulmonary and anti-allergy agents, D.J. Wolanin and J.B. Campbell
- chemotherapeutic agents, J.J. Plattner
- antibacterial agents, K.E. Brighty and P.R. McGuirk
- antiviral agents, M.M. Mansuri and J.C. Martin
- HIV protease inhibitors, D.W. Norbeck and D.J. Kempf
- radiosensitizers, M.J. Suto
- antiparasitic agents, D.M. Schmatz and J.M. Schaeffer
- function of human retrovirus regulatory proteins, C.A. Rosen and S.M. Ruben
- immunology, endocrinology and metabolic diseases, W.F. Michne
- chemical basis for immune mediated idiosyncratic drug hypersensitivity, M.A. Sanner and T.J. Higgins
- cholecystokinin agonists and antagonists, A.M. Nadzan and J.F. Kerwin
- recent advances in bone metabolism and osteoporosis research, T.J. Caggiano, et al
- mechanism-based immunosuppressants, J.R. Luly
- topics in biology, K.B. Seamon
- cytokin receptors, D.L. Urdal
- amyloidogenesis as a therapeutic target in Alzheimer's disease, B.D. Greenberg and F.J. Kezdy
- bacterial adhesins, J. London
- regulation of the ras GTPase cycle, G. Bollag, et al
- topics in drug design and discovery, M.C. Venuti
- the search for molecular diversity (1) natural products, L.J. Nisbet and P.J. Hylands
- the search for molecular diversity (2) recombinant and synthetic randomized peptide libraries, W.J. Dower and S.P.A. Fodor
- receptor modeling by distance geometry, J.M. Blaney and J.S. Dixon
- sequence-defined oligonucleotides as potential therapeutics, M.D. Matteucci and N. Bischofberger
- trends and perspectives, J.A. Bristol
- to market, to market - 1990, J.D. Strupczewski, et al
- perspectives on human gene therapy, G.J. Nabel and E.G. Nabel.
- Volume
-
v. 27 ISBN 9780120405275
Description
Table of Contents
- Part 1 Agents: the decade of the brain, M. Williams
- pharmacological intervention in sleep and circadian processes, J.D. Miller
- advances in central serotoninergics, A.G. Romero and A.B. McCall
- traumatic and ischemia/reperfusion injury to the CNS, J.M. McCall and J.A. Panetta
- trophic factors and their receptors in the CNS, S. Rosenberg
- antipsychotics, L.D. Wise and T.G. Heffner. Part 2 Cardiovascular and pulmonary agents: angiotensin/renin modulators, W.J. Greenlee and P.K.S. Siegl
- EDRF, an emerging target for drug design, J.F. Kerwin, Jr
- endogenous vasoactive peptides, A.M. Doherty
- recent advances in antiarrhythmic therapy - potassium channel antagonists, M.G. Cimini and J.K. Gibson
- future antithrombotic therapy, J.A. Jakubowski, et al
- pulmonary and anti-allergy agents, R.T. Jacobs, et al. Part 3 Chemotherapeutic agents: antibacterial agents, targets, and approaches, M.J. Suto, et al
- genetic engineering of antibiotic producing organisms, L. Katz and C.R. Hutchinson
- inhibitors of angiogenesis, M.A. Mitchell and J.W. Wilks
- recent advances in antifungal agents, J.F. Barrett and D.H. Klaubert
- progress in antimicrobial peptides, S.W. Blondelle and R.A. Houghten
- protein tyrosine kinases and cancer, E.M. Dobrusin and D.W. Fry. Part 4 Immunology, endocrinology, and metabolic diseases: monoclonal antibodies in therapy, G.A. Heavner
- techniques for determining epitopes for antibodies and T-cell receptors, D.C. Benjamin and S.S. Perdue
- potential therapeutic modifiers of the complement cascade, W.K. Hagmann and R.D. Sindelar
- cytokine modulation as medicinal chemistry target, K. Cooper and H. Masamune
- recent advances in the discovery and development of potential antidiabetic agents, J.R. Colca and S.P. Tanis. Part 5 Topics in biology: the role of homeobox genes in vertebrate embryonic development, K. Mahon and M. Jamrich
- emerging therapies for cystic fibrosis, A.E. Smith
- the guanylyl cyclase family of receptor/enzymes, H.-J. Fulle and D.L. Garbers
- HIV vaccine development - from empiricism to medicinal chemistry, M.J. Glass and W.C. Kogg
- inositol triphosphate receptors, S.K. Joseph. Part 6 Topics in drug design and discovery: macromolecular X-ray crystalloglraphy and NMR as tools for structure-based drug design, J.W. Erickson and S.W Fesik. Part contents.
- Volume
-
v. 28 ISBN 9780120405282
Description
Table of Contents
- Volume
-
v. 29 ISBN 9780120405299
Description
Table of Contents
- Part 1 CNS agents: third generation antidepressants
- neuronal cell death
- muscarinic agonists and antagonists
- animal engineering in neurobiology
- dopamine D3 and D4 receptor ligands and pharmacology
- excitatory amino acid research. Part 2 Cardiovascular and pulmonary agents: endothelin receptor antagonists
- treatment of asthma and allergy
- nitric oxide synthase
- thrombolytic agents
- antithrombotic and anti-inflammatory agents. Part 3 Chemotherapeutic agents: antibacterial agents
- HIV reverse transcriptase inhibitors
- HIV protease inhibitors
- ras oncogene. Part 4 Immunology, endocrinology and metabolic diseases: non-immunophilin-related immunosuppressants
- phosphodiesterase inhibitors as antiasthmatic agents
- human leukocyte elastase inhibitors
- interleukin-1
- cell adhesion and carbohydrates
- control of androgen action. Part 5 Topics in biology: transcription factor NF-kB
- translational control of gene expression
- protein kinases and photophatases
- transgenic and gene targeting technology
- osteoporosis. Part 6 Topics in drug design and discovery: adenylate cyclase subtypes
- advances in antisense technology
- prediction of human drug metabolism
- humanized monoclonal antibodies
- ethnobotany. Part 7 Trends and perspectives: to market, to market - 1993
- appendices.
- Volume
-
v. 30 ISBN 9780120405305
Description
Table of Contents
- Central nervous system diseases
- cardiovascular and pulmonary diseases
- cancer and infectious diseases
- immunology, endocrinology and metabolic diseases
- topics in biology
- topics in drug design and discovery
- trends and perspectives.
- Volume
-
v. 31 ISBN 9780120405312
Description
Table of Contents
- Central nervous system diseases
- cardiovascular and pulmonary diseases
- cancer and infectious diseases
- immunology, endocrinology and metabolic diseases
- topics in biology
- topics in drug design and discovery
- trends and perspectives.
- Volume
-
v. 32 ISBN 9780120405329
Description
Table of Contents
- Part 1 Central nervous system diseases, D.W. Robertson: recent advances in migraine therapy, T. Branchek and J.E. Audia
- Alzheimer's disease - recent advances on the amyloid hypothesis, V. John et al
- obesity - leptin-neuropeptide Y interactions in the control of body weight, D.R. Gehlert and M. Heiman
- melatonin receptor ligands and their potential clinical applications, C.D. Mahle et al
- corticotrophin-releasing hormone (CRH) receptors and the discovery of selective non-peptide CRH1 antagonists, P.J. Gilligan et al
- recent advances in neurokinin receptor antagonists, S.G. Mills. Part 2 Cardiovascular and pulmonary diseases, A.M. Doherty: endothelin inhibitors, X.-M. Cheng et al
- antithrombotics/serine proteases, W.C. Ripka and G.P. Vlasuk
- leukotriene modulators as therapeutic agents in asthma and other inflammatory diseases, R.L. Bell et al
- emerging opportunities in the treatment of atherosclerosis, C.M. Hayward and M.J. Bamberger. Part 3 Cancer and infectious diseases, J.J. Plattner: new approaches and agents to overcome bacterial resistance, J.M. Domagala and J.P. Sanchez
- bacterial genomics and the search for novel antibiotics, L. Katz et al
- resistance to antiretroviral drug therapy, A. Molla and W.E. Kohlbrenner
- non-HIV antiviral agents, S.H. Krawczyk and N. Bischofberger
- recent advances in antifungal agents, P.A. Lartey and C.M. Moehle
- angiogenesis inhibitors, D. Powell et al
- chemical inhibitors of cyclin-dependent kinases, K.G. Coleman et al. Part 4 Immunology, endocrinology and metabolic diseases, W.K. Hagmann: T lymphocyte potassium channel blockers, J.C. Kath et al
- male contraception, D.W. Combs
- new dermatological agents for the treatment of psoriasis, S. Nagpal and R.A.S. Chandraratna
- selective cyclooxygenase-2 inhibitors, P. Prasit and D. Riendeau
- growth hormone secretagogues, R.P. Nargund and L.H.T. Van der Ploeg. Part 5 Topics in biology, W.W. Wong: novel gene switches for the regulation of gene expression
- agents that block TNF-I synthesis or activity, R.A. Black et al
- nuclear orphan receptors - scientific progress and therapeutic opportunities, D.W. Robertson et al. Part 6 Topics in drug design and discovery, G.L. Trainor: discovery and identification of lead compounds from combinational mixtures, B.A. Beutal
- electrospray mass spectrometric characterization of adducts between therapeutic agents and proteins, C. Fenselau
- nonpeptide agonists for peptide receptors - lessons from ligands, E.E. Sugg
- natural products research and pharmaceuticals in the 1990s, S.K. Wrigley and M.I. Chicarelli-Robinson
- inhibition of cytochrome P-450 and implications in drug development, J.H. Lin and A.Y.H. Lu. Part 7 Trends and perspectives, J.A. Bristol: to market, to market - 1996, P. Galatsis.
- Volume
-
v. 33 ISBN 9780120405336
Description
Table of Contents
- Volume
-
v. 34 ISBN 9780120405343
Description
Table of Contents
- Section Editor: D.W. Robertson, Central Nervous System Diseases. Section Editor: W.J. Greenlee, Cardiovascular and Pulmonary Diseases. Section Editor: J.J. Plattner, Cancer and Infectious Diseases. Section Editor: W.K. Hagmann, Immunology, Endocrinology, and Metabolic Diseases. Section Editor: W.W. Wong, Topics in Biology. G.L. Trainor, Topics in Drug Design and Discovery. Section Editor: A.M. Doherty, Trends and Perspectives.
- D.A. Evrard and B.L. Harrison, Recent Approaches to Novel Antidepressant Therapy. J.R. McCarthy, S.C. Heinrichs, and D.E. Grigoriadis, Recent Progress in Corticotropin-Releasing Factor Receptor Agents. C.E. Augelli-Szafran, L.C. Walker, and H. LeVine III, -Amyloid as a Target for Alzheimer's Disease Therapy. A.W Stamford and E.M. Parker, Recent Advances in the Development of Neuropeptide Y Receptor Antagonists. K.S. Takaki and J.R. Epperson, Pharmacological Interventions in the Sleep Process. C. Swain and N.M.J. Rupniak, Progress in the Development of Neurokinin Antagonists.
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v. 35 ISBN 9780120405350
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v. 36 ISBN 9780120405367
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v. 37 ISBN 9780120405374
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v. 38 ISBN 9780120405381
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v. 39 ISBN 9780120405398
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v. 40 ISBN 9780120405404
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v. 41 ISBN 9780120405411
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v. 42 ISBN 9780123739124
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v. 43 ISBN 9780123743442
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- Part I. Central Nervous System Diseases C ROBICHAUD Chapter 1 Recent Advances in Corticotropin Releasing Factor Receptor Antagonists Carolyn D. Dzierba
- Richard A. Hartz
- Joanne J. Bronson Chapter 2 Recent Advances on the 5-HT5A, 5-HT6 and 5-HT7 Receptors Brock T. Shireman, Pascal Bonaventure and Nicholas I. Carruthers Chapter 3 Recent Advances in Voltage Gated Sodium Channel Blockers: Therapeutic Potential as Drug Targets in the CNS Andreas Termin, Esther Martinborough and Dean Wilson Chapter 4 Medication Development for the Treatment of Substance Abuse Brian Fulton Part II. Cardiovascular and Metabolic Diseases - STAMFORD Chapter 5 GPR40 (FFAR1) Modulators Julio C. Medina and Jonathan B. Houze Chapter 6 Rho-Kinase Inhibitors for Cardiovascular Disease Robert A. Stavenger Chapter 7 LXR Agonists for the Treatment of Atherosclerosis - Recent Highlights Jonathan Bennett, Andrew Cooke, Heather J. McKinnon and Olaf Nimz Chapter 8 Glucagon Receptor Antagonists for Type II Diabetes DuaneE. DeMong, Michael W. Miller and Jean Lachowicz Part III. Inflammation / Pulmonary / GI C BARRISH Chapter 9 Advances Towards Dissociated Non-Steroidal Glucocorticoid Receptor Agonists John Regan, Hossein Razavi, David Thomson Chapter 10 Advances in the Discovery of IkB Kinase Inhibitors William J. Pitts and James Kempson Chapter 11 Protease Inhibitors for the Potential Treatment of Chronic Obstructive Pulmonary Disease and Asthma Weimin Liu and Eugene Hickey Part IV. Oncology - MYLES Chapter 12 mTor Inhibitors in Oncology Jeroen Verheijen, Ker Yu and Arie Zask Chapter 13 Oncology Drug Targets in the Sphingomyelin Signaling Path Bill Garland, Amy Cavalli and Genevive Hansen Part V. Infectious Diseases - Primeau Chapter 14 Inhibitors of Respiratory Syncytial Virus Malcolm Carter and G. Stuart Cockerill Chapter 15 Recent Developments in |A-Lactamases and Inhibitors Tarek S. Mansour, Patricia A. Bradford and Aranapakam M. Venkatesan Chapter 16 Recent Development in the Treatment of Clostridium Difficile Associated Disease (CDAD) Xicheng Sun, Joseph Guiles and Nebojsa Janjic Chapter 17 Recent Advances in the Discovery of Hybrid Antibacterial Agents Mike Barbachyn Part VI. Topics in Biology - LOWE Chapter 18 Recent Renaissance of Prostaglandin Research Robert Burk Chapter 19 Human Exposure and Dose Projections Punit H. Marathe, Christine Huang and A. David Rodrigues Chapter 20 Modeling Networks of Glycolysis, Overall Energy Metabolism and Drug Metabolism under a Systems Biology Approach Zoltan Sarnyai and Laszlo G. Boros Part VII. Topics in Drug Design and Discovery C DESAI Chapter 21 Contrasting the Gastrointestinal Tracts of Mammals: Factors that Influence Absorption John DeSesso and Amy Lavin Williams Chapter 22 The Emerging Utility of Co-Crystals in Drug Discovery and Development Nicholas Meanwell Chapter 23 Pregnane X Receptor: Prediction and Attenuation of Human CYP3A4 Enzyme Induction and Drug-Drug Interactions Michael W. Sinz Chapter 24 Formulation in Drug Discovery Robert Strictly Part VIII. To Market, To Market Chapter 25 To Market, To Market - 2007 Shridhar Hegde and Michelle Schmidt
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v. 44 ISBN 9780123747662
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v. 45 ISBN 9780123809025
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v. 46 ISBN 9780123860095
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v. 47 ISBN 9780123964922
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- Personal Essay Reflections on Medicinal Chemistry at Merck, West Point Paul S. Anderson My Path in Seeking New Medicines Peter R. Bernstein Tales of Drug Discovery M. Ross Johnson I. Central Nervous System Diseases Section Editor: Albert J. Robichaud
- Sage Therapeutics, Inc. Cambridge, Massachusetts Recent Developments in Targeting Neuroinflammation in Disease Allen T. Hopper, Brian M. Campbell, Henry Kao, Sean A. Pintchovski and Roland G. W. Staal Secretase Inhibitors and Modulators as a Disease Modifying Approach Against Alzheimer's Disease Harrie J. M. Gijsen and Francois P. Bischoff mGluR2 Activators and mGluR5 Blockers Advancing in the Clinic for Major CNS Disorders Sylvain Celanire, Guillaume Duvey, Sonia Poli and Jean-Philippe Rocher NMDA Antagonists of GluN2B Subtype and Modulators of GluN2A, GluN2C and GluN2D Subtypes - Recent Results and Developments Kamalesh B. Ruppa, Dalton King and Richard Olson Recent Advances in the Development of PET and SPECT Tracers for Brain Imaging Lei Zhang and Anabella Villalobos II. Cardiovascular and Metabolic Diseases Section Editor: Andy Stamford, Merck Research Laboratories, Kenilworth, New Jersey Case History: EliquisTM (Apixaban), a Potent and Selective Inhibitor of Coagulation Factor Xa for the Prevention and Treatment of Thrombotic Diseases Donald J. P. Pinto, Pancras C. Wong, Robert M. Knabb and Ruth R. R. Wexler AMPK Activation in Health and Disease Iyassu K. Sebhat and Robert W. Myers Type-2 Diabetes and Associated Co-Morbidities as an Inflammatory Syndrome Juan C. Jaen, Jay P. Powers and Tim Sullivan Beyond PPARs & Metformin: New Insulin Sensitizers for the Treatment of Type 2 Diabetes Philip A. Carpino and David Hepworth III. Inflammatory Pulmonary and Gastrointestinal Diseases Section Editor: David S. Weinstein, Bristol-Myers Squibb R&D, Princeton, New Jersey Recent Advances in the Discovery and Development of Sphingosine-1-Phosphate-1 Receptor Agonists Alaric J. Dyckman Bifunctional Compounds for the Treatment of COPD Gary Phillips and Michael Salmon Inflammatory Targets for the Treatment of Atherosclerosis Robert O. Hughes, Alessandra Bartolozzi and Hidenori Takahashi IV. Oncology Section Editor: Shelli R. McAlpine, School of Chemistry, University of New South Wales, Sydney, Australia Nanotechnology Therapeutics in Oncology - Recent Developments and Future Outlook Paul F. Richardson Small-Molecule Antagonists of Bcl-2 Family Proteins Sean P. Brown and Joshua P. Taygerly Notch Pathway Modulators as Anti-Cancer Chemotherapeutics Vibhavari Sail and M. Kyle Hadden Anaplastic Lymphoma Kinase (ALK) Inhibitors for the Treatment of ALK-Positive Cancers Kazutomo Kinoshita, Nobuhiro Oikawa and Takuo Tsukuda V. Infectious Diseases Section Editor: John Primeau, Westford, Massachusetts Recent Advances in the Discovery of Dengue Virus Inhibitors Jeremy Green, Upul Bandarage, Kate Luisi and Rene Rijnbrand Non Fluoro-Quinolone Based Inhibitors of Mycobacterial Type II Topoisomerase as Potential Therapeutic Agents for TB Pravin S. Shirude and Shahul Hameed HCV Inhibition Mediated through the Nonstructural Protein 5A (NS5A) Replication Complex Robert Hamatake, Andrew Maynard and Wieslaw M. Kazmierski VI. Topics in Biology Section Editor: John Lowe, JL3Pharma LLC, Stonington, Connecticut Antibody-Drug Conjugates for Targeted Cancer Therapy Victor S. Goldmacher, Thomas Chittenden, Ravi V. J. Chari, Yelena V. Kovtun and John M. Lambert 3D Cell Cultures: Mimicking in Vivo Tissues for Improved Predictability in Drug Discovery Indira Padmalayam and Mark J. Suto Virally Encoded G Protein-Coupled Receptors: Overlooked Therapeutic Opportunities? Nuska Tschammer Recent Advances in Wnt/b-Catenin Pathway Small Molecule Inhibitors Daniel D. Holsworth and Stefan Krauss VII. Topics in Drug Design and Discovery Section Editor: Peter R. Bernstein, PhaRmaB LLC, Rose Valley, Pennsylvania Targeted Covalent Enzyme Inhibitors Mark C. Noe and Adam M. Gilbert Drug Design Strategies for GPCR Allosteric Modulators P. Jeffrey Conn, Scott D. Kuduk and Dario Doller Progress in the Development of Non-ATP Competitive Protein Kinase Inhibitors for Oncology Campbell McInnes VIII. Trends Section Editor: Joanne Bronson, Bristol-Myers Squibb, Wallingford, Connecticut New Chemical Entities Entering Phase III Trials in 2011 Gregory T. Notte To Market, To Market - 2011Joanne Bronson, Murali Dhar, William Ewing and Nils Lonberg
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v. 48 ISBN 9780124171503
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v. 49 ISBN 9780128001677
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v. 50 ISBN 9780128130698
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v. 51 ISBN 9780128151433
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v. 52 ISBN 9780128175569
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v. 53 ISBN 9780128198667
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