書誌事項

Carcinogenesis

editors, Mortimer L.Mendelsohn, Richard J. Albertini

(Progress in clinical and biological research, v. 340 . Mutation and the environment ; pt. D)

Wiley-Liss, c1990

  • : set

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注記

"Proceedings of the Fifth International Conference on Environmental Mutagens, Held in Cleveland, Ohio, July 10-15, 1989"--t.p.

Includes bibliographical refernces

内容説明・目次

巻冊次

: set ISBN 9780471567905

内容説明

Identifies obstacles to effective DSS processing, demonstrating how database machines provide efficient and potent paths around these obstructions. Using Teradata as an example, it explains the benefit of database devices, how they support atomic level data, manage large amounts of data, expand economically as atomic data level grows and how they access such diverse systems as DB2 and LANs.
巻冊次

ISBN 9780471567967

内容説明

One of a series of five volumes, each offering a broad summary of the field with emphasis on new research and future prospects and with the parallel aspects of environmental mutagenesis. This volume examines cancer mechanisms, tests for carcinogens and screens for genotoxicity.

目次

  • Part 1 Oncogenes and related cancer mechanisms: oncogene activation during multi-stage carcinogenesis
  • organ specific genotoxicity and carcinogenicity. Part 2 Promotion and nongenotoxic mechanisms: promotion and progression in carcinogenesis
  • role of free radicals in tumor promotion and progression by benzoyl peroxide. Part 3 Cell transformation: malignant transformation of human fibroblasts on oncogene transfection or carcinogen treatment
  • chemical-induced transformation in BALB/c-373 cells
  • relationship between in vitro transformation and cytotoxicity, carcinogenesis and genotoxicity. Part 4 Short term testing: the assembley and analysis of short-term genotoxicity test data - an ICPEMC committee 1 working paper. Part 5 Species extrapolation of carcinogenicity and mutagenicity: species comparisons regarding comparative metabolism of two structurally similar phenylenediamines (HC blue 1 and HC blue 2)
  • combined in vivo DNA binding and tumor dose-response studies to investigate the molecular dosimetry concept. Part 6 Rapid screens for genotoxicity: automation of screening assays for DNA damaging agents which induce the SOS response
  • evaluation of the bioluminescence assays as screens for genotoxic chemicals. Index
  • standing order category
  • biology.

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詳細情報

  • NII書誌ID(NCID)
    BA11404413
  • ISBN
    • 0471567965
    • 0471567906
  • LCCN
    90011953
  • 出版国コード
    us
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    New York
  • ページ数/冊数
    xviii, 403 p.
  • 大きさ
    24 cm
  • 分類
  • 件名
  • 親書誌ID
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