The biology of hematopoiesis : proceedings of the 15th Annual Frederick Stohlman, Jr., M.D., Memorial Symposium : an International Symposium on the Biology of Hematopoiesis, held in Cambridge, Massachussetts, October 15-20, 1989
著者
書誌事項
The biology of hematopoiesis : proceedings of the 15th Annual Frederick Stohlman, Jr., M.D., Memorial Symposium : an International Symposium on the Biology of Hematopoiesis, held in Cambridge, Massachussetts, October 15-20, 1989
（Progress in clinical and biological research, v. 352）
Wiley-Liss, c1990
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This work presents technical material on the most recent developments in the field of blood cell production, including the isolation and purification of haematopoietic stem cells, their characteristics in gene transfer and expression, and the applications of purified stem cells and recombinant growth factors in bone marrow therapy. Comprehensive in scope, the book includes reviews of the general history and status of the entire field. Leading researchers and clinicians cover highly specialized topics, including tissue culture systems and cellular requirements for haematopoietic differentiation; growth factor receptors and the molecular and cellular biology of haematopoiesis; gene expression and transfer in haematopoietic stem cells, and regulation of haematopoietic growth factors.There is also a section on the ethics of genetic manipulation in haematopoietic therapy with perspectives from both scientists and the clergy.
目次
- Defined Tissue Culture Systems and Purified Stem Cells
- Matrix Components and Stromal Regulation of Hematopoiesis
- Megakaryocytopoiesis
- Hematopoietic Growth Factor Receptors
- Second Messenger Signaling Systems
- Transcriptional and Translational Control of Hematopoiesis
- Gene Transfer and Expression in Hematopoietic Cells
- Ethical Considerations Regarding Potentials of Human Gene Therapy
- Biology of Hematopoiesis and Implications for Therapy
- Radiation Injury and Bone Marrow Function
- Clinical Trials of Hematopoietic Growth Factors.
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