Effects of therapy on biology and kinetics of the residual tumor : proceedings of an International Symposium on the Effects of Therapy on the Biology and Kinetics of the Surviving Tumor, held in Vancouver, British Columbia, Canada, February 15-18, 1989
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Bibliographic Information
Effects of therapy on biology and kinetics of the residual tumor : proceedings of an International Symposium on the Effects of Therapy on the Biology and Kinetics of the Surviving Tumor, held in Vancouver, British Columbia, Canada, February 15-18, 1989
(Progress in clinical and biological research, v. 354)
Wiley-Liss, c1990
- pt. A
- pt. B
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Note
Includes bibliographical references
Includes index
Contents of Works
- pt. A. Pre-clinical aspects
- pt. B. Clinical aspects
Description and Table of Contents
- Volume
-
pt. A ISBN 9780471568292
Description
This volume examines the effectiveness of different cancer treatment modalities as applied under a range of individual conditions. It specifically deals with kinetics, growth factors, metastases and immunity, and genetic regulation.
Table of Contents
- Partial table of contents:
- Review of the Effects of Therapy on the Biology and Kinetics of the Surviving Tumor, Part I (J. Ragaz)
- KINETICS
- Effects of the Initial Chemotherapy on Subsequent Therapy (L. Simpson-Herren & P. Noker)
- Proliferative and Vascular Responses to Cytoreduction in Solid Tumor Models (P. Braunschweiger)
- KINETICS AND TREATMENT DESIGN
- Tumor Differences, Drug Differences, Treatment Design Differences, and Effects on Therapeutic Outcome (Degree and Duration of Therapeutic Response) (H. Skipper)
- Genetic and Kinetic Factors in the Drug Resistance of Micrometastatic Disease (J. Goldie)
- Biology of Residual Breast Cancer After Therapy: A Kinetic Interpretation (L. Norton)
- GROWTH FACTORS
- Growth Control of Normal and Malignant Breast Epithelium (M. Lippman & R. Dickson)
- Inhibitors of Bombesin-Stimulated Intracellular Signals: Interruption of an Autocrine Pathway as a Therapeutic Strategy in Small Cell Lung Carcinoma (E. Sausville, et al.)
- GENETIC REGULATION OF TUMOR GROWTH
- Growth Control in Leukemia (A. Eaves & C. Eaves)
- METASTASES AND IMMUNITY
- Macrophages, Metastasis and Immunity (N. Phillips)
- Development of Myelorestorative and Immunotherapeutic Properties of Cytokines (J. Talmadge, et al.)
- MICROENVIRONMENT, DIFFERENTIATION, AND CHEMOPREVENTION
- Cellular Maturation and Oncogene Expression During Drug-Induced Differentiation In Vitro: A Brief Review (J. Biedler, et al.)
- Leaky Tumor Vessels: Consequences for Tumor Stroma Generation and for Solid Tumor Therapy (H. Dvorak)
- Embryonic Mechanisms for Abrogating the Malignancy of Cancer Cells (R. Parchment, et al.)
- SUMMARY
- Index.
- Volume
-
pt. B ISBN 9780471568308
Description
The two volumes of this work examine the effectiveness of different cancer treatment modalities as applied under a range of individual conditions and, further, discusses the behaviour of residual tumours that survive such treatments. Serving as both a source of information and a guide to future research, this work deals with pre-clinical tumours, covering the short and long-term consequences of various techniques on both the host patient and the carcinoma itself. Among the many pre-clinical issues discussed in Part A are kinetics, growth factors, metastases and immunity, and genetic regulation. Part B treats clinical aspects such as biological response modifiers, radiobiology, autologous bone marrow transplantation and more.
Table of Contents
- Partial table of contents:
- BIOLOGICAL RESPONSE MODIFIERS
- Tumor Treatment and Cytokines (J. Schrader, et al.)
- Towards Improved Cancer Therapy Using Subcutaneously Administered Hemopoietic Colony Stimulating Factors (G. Morstyn, et al.)
- Mechanisms of Action of Interferon (H. Ozer)
- RADIOBIOLOGY
- The Growth Kinetics of Clonogenic Tumor Cells That Survive Radiation Therapy (R. Kallman & C. Hughes)
- Microenvironmental Changes in Irradiated Tumors (S. Rockwell & C. Hughes)
- CLINICAL ASPECTS OF THERAPY--INTEGRATION OF DOSE INTENSITY KINETICS AND BIOLOGY WITH TREATMENT PLANNING
- Modeling the Effect of Chemotherapy Intensity (C. Coppin, et al.)
- Comments on Kinetics and Biology of the Residual Cancer, and on Relevant Therapeutic Strategies Based on These Phenomena (J. Ragaz)
- AUTOLOGOUS BONE MARROW TRANSPLANTATION
- Autologous Bone Marrow Transplantation for Hematologic Cancer (G. Phillips)
- Use of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) to Support Intensive Chemotherapy (H.-G
- Klingemann)
- CONSEQUENCES OF THERAPY
- Induction of Secondary Neoplasms by the Treatment of Malignant Disease: Lessons from Hodgkin's Disease (J. Connors)
- Overview of Adjuvant Radiotherapy for Breast Cancer (J. Cuzick)
- Chemotherapy Schedules: Impact on Treatment Outcomes and Quality of Life (M. Tattersall)
- SUMMARY
- Index.
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