Mass spectrometry
著者
書誌事項
Mass spectrometry
（Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 193）
Academic Press, c1990
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注記
Includes bibliographical footnotes and indexes
内容説明・目次
内容説明
This volume presents a compilation of experimental methods and principles, with detailed protocols and examples. Techniques which have demonstrated value in problem-solving are included.
Intended for biochemists, cell biologists, microbiologists, pharmacologists, biomedical scientists, biophysicists, analytical chemists, and physiologists, this book focuses on mass spectrometry. Topics discussed include the methods of ionization, liquid chromatography, continuous flow fast atom bombardment mass spectrometry, collision-induced dissociation, enzymatic and chemical digestion of proteins, and constituents of nucleic acids. Other titles in this series include Guide to Yeast Genetics and Molecular Biology and Retinoids, Part B: Cell Differentiation and Clinical Applications.
目次
J.A. McCloskey, Introduction.
General Techniques:
R.J. Cotter and A.G. Harrison, Methods of Ionization.
K.R. Jennings and G.G. Dolnikowski, Mass Analyzers.
S. Evans, Detectors.
J.T. Watson, Selected Ion Measurements.
M.L. Vestal, Liquid Chromatography-Mass Spectrometry.
M.L. Gross, Tandem Mass Spectrometry: Multisector Magnetic Instruments.
R.A. Yost and R.K. Boyd, Tandem Mass Spectrometry: Quadrupole and Hybrid Instruments.
E. De Pauw, Matrix Selection for Liquid Secondary Ion and Fast Atom Bombardment Mass Spectrometry.
R.M. Caprioli, Continuous-Flow Fast Atom Bombardment Mass Spectrometry.
M.L. Gross and R.N. Hayes, Collison-Induced Dissociation.
R.D. Macfarlane, Principles of Californium-252 Plasma Desorption Mass Spectrometry Applied to Protein Analysis.
F. Hillenkamp and M. Karas, Mass Spectrometry of Peptides and Proteins by Matrix-Assisted Ultraviolet Laser Desorption/Ionization.
K. Biemann, Utility of Exact Mass Measurements.
R.M. Milberg, Selection and Use of Mass Reference Standards.
D.R. Knapp, Chemical Derivatization for Mass Spectrometry.
J.A. McCloskey, Introduction of Deuterium by Exchange for Measurement by Mass Spectrometry.
R.C. Murphy and K.L. Clay, Preparation of Labeled Molecules by Exchange with Oxygen-18 Water.
Peptides and Proteins:
K. Biemann, Peptides and Proteins: Overview and Strategy.
T.D. Lee and J.E. Shively, Enzymatic and Chemical Digestion of Proteins for Mass Spectrometry.
D.L. Smith and Z. Zhou, Strategies for Locating Disulfide Bonds in Proteins.
K.L. Stone, J.I. Elliott, G. Peterson, W. McMurray, and K.R. Williams, Reversed-Phase High-Performance Liquid Chromatography for Fractionation of Enzymatic Digests and Chemical Cleavage Products of Proteins.
C.G. Edmonds and R.D. Smith, Electrospray Ionization Mass Spectrometry.
P. Roepstorff, Sample Preparation for Plasma Desorption Mass Spectrometry.
I. Jardine, Molecular Weight Analysis of Proteins.
K. Biemann, Sequencing of Peptides by Tandem Mass Spectrometry on High-Energy Collision-Induced Dissocation.
B.W. Gibson and P. Cohen, Liquid Secondary Ion Mass Spectrometry of Phosphorylated and Sulfated Peptides and Proteins.
S.A. Carr, J.R. Barr, G.D. Roberts, K. Anumula, and P.B. Taylor, Identification of Attachment Sites and Structural Classes of Asparagine-Linked Carbohydrates in Glycoproteins.
H.A. Scoble and S.A. Martin, Characterization of Recombinant Proteins.
Glycoconjugates:
R.A. Laine, Glycoconjugates: Overview and Strategy.
C.G. Hellerqvist, Linkage Analysis Using Lindberg Method.
G.R. Gray, Linkage Analysis Using Reductive Cleavage Method.
A.-S. Angel and B. Nilsson, Linkage Positions in Glycoconjugates by Periodate Oxidation and Fast Atom Bombardment Mass Spectrometry.
D.R. M~aduller, B. Domon, and W.J. Richter, Tandem Mass Spectrometry in Structural Characterization of Oligosaccharide Residues in Glycoconjugates.
B.E. Samuelsson, W. Pimlott, and K.-A. Karlsson, Mass Spectrometry of Mixtures of Intact Glycosphingolipids.
A. Dell, Preparation and Desorption Mass Spectrometry of Permethyl and Peracetyl Derivatives of Oligosaccharides.
L. Poulter and A.L. Burlingame, Desorption Mass Spectrometry of Oligosaccharides Coupled with Hydrophobic Chromophores.
A.L. Burlingame and B.L. Gillece-Castro, Oligosaccharide Characterization with High-Energy Collision-Induced Dissociation Mass Spectrometry.
J. Peter-Katalini~aac and H. Egge, Desorption Mass Spectrometry of Glycosphingolipids.
G.C. Hansson and H. Karlsson, High-Mass Gas Chromatography-Mass Spectrometry.
C.E. Costello and J.E. Vath, Tandem Mass Spectrometry of Glycolipids.
Nucleotides and Nucleosides:
J.A. McCloskey, Constituents of Nucleic Acids: Overview and Strategy.
P.F. Crain, Preparation and Enzymatic Digestion of DNA and RNA for Mass Spectrometry.
K.H. Schram, Preparation of Trimethylsilyl Derivatives of Nucleic Acid Components for Analysis by Mass Spectrometry.
S.C. Pomerantz and J.A. McCloskey, Analysis of RNA Hydrolyzates by Liquid Chromatography-Mass Spectrometry.
J.A. McCloskey, Electron Ionization Mass Spectra of Trimethylsilyl Derivatives of Nucleosides.
M. Dizdaroglu, Gass Chromatography-Mass Spectrometry of Free Radical-Induced Products of Pyrimidines and Purines in DNA.
P.F. Crain, Analysis of 5-Methylcytosine in DNA by Isotope Dilution Gas Chromatography-Mass Spectrometry.
Appendixes:
Isotopic Exact Masses and Abundances.
Reference Ions for Exact Mass Measurements.
Matrix Cluster Ions.
Calculation of Isotopic Abundance Patterns.
Nomenclature for Peptide Fragment Ions.
Residue Mass for Peptides.
Author Index.
Subject Index.
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