Receptor-effector coupling : a practical approach

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Bibliographic Information

Receptor-effector coupling : a practical approach

edited by E.C. Hulme

(The practical approach series)

IRL Press at Oxford University Press, c1990

  • : hard
  • : pbk

Available at  / 23 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Volume

: hard ISBN 9780199630943

Description

This is one of a trio of books covering the major aspects of hormone and neurotransmitter-receptor-ligand interactions, receptor biochemistry, and receptor-response coupling. The range of techniques covered is appropiate to the receptors whose biochemistry is the subject of the companion book, "Receptor Biochemistry: A Practical Approach".

Table of Contents

  • K. Oldham: Polyphosphoinositide turnover
  • D. Poyner: Receptor-G protein complexes in solution
  • P. Sternweis, & I.H. Pang: Preparation of G-proteins and their subunits
  • R. Cerione: Reconstitution of B-adrenergic receptor-G-protein interactions
  • K. Haga, & T. Haga: Reconstitution of muscarinic receptor-G-protein interactions
  • A. Gurney: Measurement and control of intracellular calcium
  • L. Mahadevan, & John C. Bell: Phosphate labelling studies of receptor tyrosine kinases
  • J. Benovic: Receptors as kinase substrates
  • A. Gurney: Molecular pharmacology of ion channels using the patch clamp.
Volume

: pbk ISBN 9780199630950

Description

This second book in the trio describes techniques for analysing the signalling mechanisms of neurotransmitter and hormone receptors. Specific practical guidance is provided in the measurement of the main varieties of receptor response. The book also provides a guide to the science behind the protocols, and includes contributions from some of the most active scientists in this diverse field. It is the first time that this range of techniques have been brought together in such a coordinated manner.

Table of Contents

  • K. Oldham: Polyphosphoinositide turnover
  • D. Poyner: Receptor-G protein complexes in solution
  • P. Sternweis, & I.H. Pang: Preparation of G-proteins and their subunits
  • R. Cerione: Reconstitution of B-adrenergic receptor-G-protein interactions
  • K. Haga, & T. Haga: Reconstitution of muscarinic receptor-G-protein interactions
  • A. Gurney: Measurement and control of intracellular calcium
  • L. Mahadevan, & John C. Bell: Phosphate labelling studies of receptor tyrosine kinases
  • J. Benovic: Receptors as kinase substrates
  • A. Gurney: Molecular pharmacology of ion channels using the patch clamp

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