Transgenic animals : proceedings of the Symposium on Transgenic Technology in Medicine and Agriculture
著者
書誌事項
Transgenic animals : proceedings of the Symposium on Transgenic Technology in Medicine and Agriculture
（Biotechnology series, 16）
Butterworth-Heinemann, c1991
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Transgenesis involves injecting foreign genetic material into an animal's own genetic material to either produce specific, economically significant traits or restructure the animal's biochemical systems so that it produces certain economically attractive molecules such as recombinant proteins or pharmaceuticals. This book details the techniques necessary for the production of transgenic animals and the industrial application of these techniques.
目次
- Transgenic animals - a new era in developmental biology and medicine
- determination of retroviral mutation rates using spleen necrosis virus-based vectors and helper cells
- steroid hormone receptors as transactivators of gene expression
- targeted mutagenesis in embryo-directed stem cells
- application of germ line transformation to the study of myogenesis
- regulation of expression of genes for mild proteins
- a normally silent gene of the transgene mouse major urinary protein comples is functional in transgenic mice
- the activation and silencing of gene transcription in the liver
- gene targeting embryonic stem cells
- a human multidrug-resistant cDNA (MDR1) under the control of the beta-actin promoter confers drug resistance in the bone marrow of transgenic mice
- insertion of a disease resistance gene into the chicken germline
- analysis of regulatory genes using the transgene mouse system
- regulation of expression of a class 1 MHC transgene
- generation of transgenic mice with major histocompatibility class II genes
- mice transgenic for a gene that encodes a soluble, polymorphic antigen from the major histocompatibility complex
- principles of gene transfer and the treatment of disease
- transgenic mice carrying HIV proviral DNA
- high levels of human apolipoprotein A-1 in transgenic mice result in increased levels of high-density lipo-protein cholesterol
- effects of human growth hormone on reproductive and neuroendocrine functions in transgenic mice
- enhanced growth performance in transgenic swine
- production of sheep transgenic for growth hormone genes
- production of transgenic cattle by pronuclear injection
- methods for the introduction of recombinant DNA into chicken embryos
- gene transfer in fish
- studies on transgenic fish
- gene transfer, expression and inheritance
- transgenic rats - a discussion
- patenting of animals.
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