Low dose radiation : biological bases of risk assessment
著者
書誌事項
Low dose radiation : biological bases of risk assessment
Taylor & Francis, 1989
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注記
Includes bibliographical references
内容説明・目次
内容説明
This book looks at the risks to man from exposure to low doses of radiation at low dose rates, a matter for intense scientific debate. The effects of low doses are not directly measurable in man and thus risks must be inferred from studies on populations exposed to high doses. It is this inference that is contentious. The book commences with papers by figures in the field of radiation epidemiology, reviewing the current status of studies on human populations exposed to radiation, including the survivors of the atomic bombings in Japan. The remaining papers, by researchers in the field of radiobiology, have been written in response to an invitation to address 12 questions fundamental to the interpretation of these data in terms of the effects of low doses. They represent the current status of radiobiology and its ability to address the problem.
目次
- Part 1 Review of current status of Japanese A-bomb study: the new radiation dosimetry for the A-bombs in Hiroshima and Nagasaki
- the new dose system and radiation induced cancer risks among A-bomb survivors
- radiation-related damage to the developing human brain
- the genetic effects of the atomic bombs - problems in extrapolating from somatic cell findings to risk for children
- cancer risk estimation from the A-bomb survivors - extrapolation to low doses, use of relative risk models, and other uncertainties. Part 2 Review of epidemiological studies: epidemiological studies of children irradiated in utero
- epidemiologic studies on uranium miners and other groups exposed to radon
- carcinogenesis following medical uses of ionising radiation
- cancer risks from internally deposited radium and thorotrast
- evidence from mammalian studies on genetic effects of low-level irradiation. Part 3 Risk projection models: models for projecting radiation risks in the BEIR V report
- the role of dose inhomogeneity in biological models of dose-response
- relative and absolute risk models for cancer mortality in ankylosing spondylitis patients
- epistemiological limits of risk assessments at low radiation doses. Part 4 Animal studies: the influence of physical factors on carcinogenesis in experimental animals
- age, sex and other factors in radiation carcinogenesis
- is a dose/response relationship a valid concept for the induction of leukaemia by bone-seeking alpha-emitting radionuclides
- irradiation of lymph nodes after deposition of radioactive particles in the lung. Part 5 Sensitive groups in the population: human ill health, abnormal radiation induced cytotoxicity and aberrant DNA metabolism
- radiosensitive individuals in the population
- determination of the proportion of persons in the population-at-large who ehhibit abnormal sensitivity to ionizing radiation. Part 6 Radiation effects in the lung: requirements for local dosimetry and risk evaluation in inhomogeneously irradiated organs
- lung tumour induction in mice after X-rays and neutrons. Part 7 Epidemiology and effects on the foetus. Part 8 Molecular biology and cell transformation. Part 9 Radiation quality. Part 10 Reverse dose rate effect.
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