書誌事項

Modification of tumor development in rodents

volume editors, N. Itō, H. Sugano

(Progress in experimental tumor research, vol. 33)

Karger, 1991

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注記

Includes bibliographical references

Includes index

内容説明・目次

内容説明

Human cancer is now generally accepted as being primarily the result of a multitude of interacting environmental factors. This study offers coverage of the ability of exogenous influences to modify tumourigenesis in the organs most often involved in cancer. The first theoretical section highlights the principles now thought to underlie neoplasia in rodents and how they can be applied to in vivo risk assessment. In the second section, experienced researchers discuss the modification of tumour development in the gastrointestinal tract, liver, pancreas, lung, urinary bladder, breast and skin. Both endogenous and exogenous influences and their possible interactions are considered, with emphasis placed on dietary and other factors relevant to the human situation.

目次

  • Genetic control of carcinogenesis in experimental animals, N.R.Drinkwater and L.M.Bennett
  • analysis of modifying factors in chemical carcinogenesis, S.M.Cohen
  • medium-term bioassay for carcinogens using multi-organ models, N.Ito et al
  • modification of tumour development in gastrointestinal tract, M.Takahashi and K.Imaida
  • modification of liver tumour development in rodents, B.A.Diwan et al
  • modification of tumour development in the pancreas, P.M.Pour
  • modulation of lung tumour development in rats, hamsters and mice, H.Witschi
  • modification of tumour development in the urinary bladder, S.Fukushima
  • mammary tumourigenesis, J.Russo and I.H.Russo
  • modification of multistage skin carcinogenesis in mice, J.DiGiovanni.

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