Neurotransmitter actions and interactions : proceedings of a satellite symposium of the 12th International Society for Neurochemistry Meeting, Algarve, Portugal, April 29-30, 1989

書誌事項

Neurotransmitter actions and interactions : proceedings of a satellite symposium of the 12th International Society for Neurochemistry Meeting, Algarve, Portugal, April 29-30, 1989

M.B.H. Youdim and K.F. Tipton (eds.)

(Journal of neural transmission. Supplementum, 29)

Springer-Verlag, c1990

  • New York
  • Wien

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注記

"A tribute to professor T.L. Sourkes, in the year of his 70th birthday"--P. following t.p. verso

Includes bibliographies and index

内容説明・目次

内容説明

This volume, produced as a tribute to Professor T.L. Sourkes (Montreal, Canada) in the year of his 70th birthday, brings together contributions from established experts in neurotransmitter actions and interactions. Fields covered include the actions of peptide transmitters, amino acids and excitotoxicity, and the functions and metabolism of the amine neurotransmitters.

目次

Theodore Lionel Sourkes : an appreciation.- Reflections at seventy.- The psychopharmacology of GABA synapses : update 1989.- Formation of 12-lipoxy-genase metabolites in rat cerebral cortical slices: stimulation by calcium iono-phore, glutamate and N-methyl-D-aspartate.- Role of excitatory amino acid neurotransmission in synaptic plasticity and pathology. An integrative hypothesis concerning the pathogenesis and evolutionary advantages of schizophrenia-related genes.- Neurochemical approaches to the amelioration of brain injury.- Neuronal nicotinic ?-bungarotoxin receptors.- Involvement of neuropeptide Y in neuroendocrine stress responses. Central and peripheral studies.- Peptide regulation of adrenal medullary function.- Inborn errors of carnosine and homocarnosine metabolism.- Histamine inactivation in the brain: aspects of N-methylation.- Phenylethylamine in the CNS: effects of monoamine oxidase inhibiting drugs, deuterium substitution and lesions and its role in the neuromodulation of catecholaminergic neurotransmission.- Biological model for the in vivo measurement of rate of serotonin synthesis in the brain.- Cerebral serotonin in viral encephalitis.- Retinal neurotransmitter interaction as reflected in horizontal cell spatial behaviour.- Phenolsulfotransferase (PST) and PAPS in catecholamine metabolism in human tissues: an overview.- Effect of some peptides on dopaminergic function in man.- Respective contributions of neuronal activity and presynaptic mechanisms in the control of the in vivo release of dopamine.- Investigations on auto-antibodies in Alzheimer's and Parkinson's diseases, using defined neuronal cultures.- Implantable microencapsulated dopamine (DA): prolonged functional release of DA in denervated striatal tissue.- Partial damage to nigrostriatal bundle : compensatory changes and the action of L-DOPA.- MAO and L-DOPA treatment of Parkinson's disease.- Oxidative stress: a role in the pathogenesis of Parkinson's disease.- Selectivity of melaninized nigro-striatal dopamine neurons to degeneration in Parkinson's disease may depend on ironmelanin interaction.- The effects of aging on MAO activity and amino acid levels in rat brain.- The interactions of monoamine oxidase with some derivatives of l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine (MPTP).- From moclobemide to Ro 19-6327 and Ro 41-1049: the development of a new class of reversible, selective MAO-A and MAO-B inhibitors.

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