Immobilized enzymes in medicine
Author(s)
Bibliographic Information
Immobilized enzymes in medicine
(Progress in clinical biochemistry and medicine, 11)
Springer, c1991
- : gw
- : us
Available at 1 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Description and Table of Contents
Description
The application of immobilized enzymes in medicine is the main objective of this book. The author reviews natural and synthetic carriers for enzyme immobilization, chemistry of enzyme binding, and in-vitro and in-vivo properties of immobilized enzymes. Four chapters are dedicated to clinical use of immobilized enzymes.
Table of Contents
- 1 Introduction.- 2 Enzymes in Medicine: Advantages and Disadvantages.- 2.1 Native Enzymes in Therapy and Clinical Analysis.- 2.2 Difficulties Connected with Enzyme Application in Medicine...- 2.3 How the Immobilization can Help.- 3 Immobilization of Therapeutic Enzymes.- 3.1 General Principles of Enzyme Stabilization and Immobilization.- 3.2 The Peculiarities of Enzyme Immobilization for Medical Use. Carriers and Immobilization Methods Required.- 3.3 The Fate of Immobilized Enzymes in the Body.- 3.4 Principal Types of Immobilized Enzymes in Medicine.- 4 Therapeutic Immobilized Enzymes for Parenteral Application.- 4.1 Preparations Intended for Prolonged Circulation in the Body.- 4.1.1 Enzymes Modified with Soluble Polymers.- 4.1.1.1 Carriers and Methods of Immobilization
- Properties of Immobilized Enzymes.- 4.1.1.2 Thrombolytic Therapy with Immobilized Enzymes.- 4.1.2 Artificial Cells.- 4.1.2.1 Properties and Application of Enzymes Immobilized in Semipermeable Microcapsules.- 4.1.2.2 Properties and Application of Enzymes Immobilized in Liposomes.- 4.1.2.3 Properties and Application of Enzymes Immobilized in Red Blood Cells Ghosts.- 4.2 Insoluble Immobilized Enzymes for Local Application.- 4.2.1 Slow-Release Systems and Their Classification.- 4.2.2 Polymeric Enzyme-Containing Implants and Micoparticles with Immobilized Enzymes.- 4.2.3 Enzymes for Modification of Polymeric Implants and Prosthetic Devices.- 4.3 Immobilization Principles and Drug Targeting.- 4.3.1 Aims and Tasks of Drug Targeting.- 4.3.2 Principal Systems of Drug Targeting.- 4.3.3 Direct and Indirect Conjugation of Therapeutic Enzymes with Specific Vectors.- 4.3.4 Use of Microreservoirs for Targeted Drug Transport.- 4.3.5 Enzyme Immobilization on Magnetic Carriers.- 5 Immobilized Enzymes for Extracorporeal Application.- 5.1 Immobilized Enzymes in Extracorporeal Systems.- 5.2 Dressing and Drainage Materials Containing Immobilized Enzymes
- Films, Ointments and Powders with Immobilized Enzymes in the Treatment of Wounds, Ulcers and Burns.- 6 Immobilized Enzymes in Clinical Analysis.- 6.1 Enzyme Electrodes.- 6.2 Enzyme Immunoassay.- 6.3 Immobilized Bioluminiscent Systems.- 6.4 Reactors with Immobilized Enzymes
- Miscellaneous.- 7 Conclusion.- 8 References.
by "Nielsen BookData"