Behavioural models in psychopharmacology : theoretical, industrial, and clinical perspectives

書誌事項

Behavioural models in psychopharmacology : theoretical, industrial, and clinical perspectives

edited by Paul Willner

Cambridge University Press, 1990

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注記

First publication year varies: 1991

内容説明・目次

内容説明

Behavioural models in psychopharmacology are used for different purposes. The main concern of industrial psychopharmacologists is specifically to develop new and improved drugs for the treatment of mental disorders, while basic scientists use animal models to investigate the underlying nature of such conditions. The important distinction between these different perspectives is made explicit for the first time in this book. By considering such conditions as anxiety, depression, mania and schizophrenia, feeding disorders, dementia, and drug dependence, this book provides a comprehensive and critical review of the adequacy of the behavioural procedures used by psychopharmacologists to model psychiatric disorders. Graduate students and research workers in pscyhopharmacology, from both academic and industrial spheres, as well as clinicians, will find this book of considerable interest.

目次

  • Contributors
  • Preface
  • Part I. Introduction: 1. Behavioural models in psychopharmacology P. Willner
  • Part II. Models of Anxiety: 2. Animal models of anxiety S. Green and H. Hodges
  • 3. Screening for anxiolytic drugs D. N. Stephens and J. S. Andrews
  • 4. Animal models of anxiety: a clinical perspective M. Lader
  • Part III. Models of Depression: 5. Animals models of depression P. Willner
  • 6. Screening for new antidepressant compounds W. Danysz
  • 7. The clinical relevance of animal models of depression J. F. W. Deakin
  • Part IV. Models of Eating Disorders: 8. Animal models of eating disorders A. M. J. Montgomery
  • 9. Screening methods for anorectic, anti-obesity and orectic agents J. Sepinwall and A. C. Sullivan
  • 10. Animals models of eating disorders: a clinical perspective D. V. Coscina and P. E. Garfinkel
  • Part V. Models of Mania and Schizophrenia: 11. M. Lyons
  • 12. Pharmacological evaluation of new antipsychotic drugs S. Ahlenius
  • 13. Animal models of schizophrenia and mania: clinical perspectives J. Cookson
  • Part VI. Models of Dementia: 14. Animal models of Alzheimer's disease and dementia (with an emphasis on cortical cholinergic systems) S. B. Dunnett and T. M. Barth
  • 15. Strategies for drug development in the treatment of dementia J. D. Salamons
  • 16. Dementia: the role of behavioural models H. J. Altman
  • Part VII. Models of Drug Abuse and Drug Dependence: 17. Animal models of drug abuse and dependence A. J. Goudies
  • 18. Screening for abuse and dependence liabilities D. J. Sanger
  • 19. The relevance of behavioural models of drug abuse and dependence liabilities to the understanding of drug misuse in humans R. Hartnoll
  • Index.

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