Drug-induced immune diseases
著者
書誌事項
Drug-induced immune diseases
（Drug-induced disorders, vol. 4）
Elsevier , Sole distributors for the USA and Canada, Elsevier Science Pub. Co., 1990
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Immunotoxicology is a major new area of toxicology. Recent developments in this field encompass pre-clinical (rodent) studies as well as predictive assessment. Little is known of clinical immunotoxicology. The first part of this book includes coverage of clinical patterns, diagnosis and mechanisms of drug-induced immune diseases, i.e. clinical consequences of immunodepression and immunoenhancement, (immuno-allergic and pseudo-allergic) hypersensitivity reactions, and auto-immune diseases. The second part includes drug by drug coverage of immunotoxicity as reported in the medical literature.
目次
Foreword. Part I. Clinical Patterns, mechanisms and diagnosis. 1. Immunotoxicology and drug-induced immunotoxic side-effects. A. Definition and scope of immunotoxicology. B. Drug-induced immunotoxic side-effects. C. Relevance of drug-induced immune diseases. 2. Clinical aspects of drug-induced immune diseases. A. Clinical aspects of drug-induced immune dysfunctions. B. Clinical aspects of drug hypersensitivity reactions. 3. Mechanisms and diagnosis of drug-induced immune diseases. A. Immunosuppression and its consequences. B. Immunostimulation and its consequences. C. Immune dysregulation and auto-immune diseases. D. Hypersensitivity. Part II. Individual agents. 4. Anesthetics and muscle relaxants. A. General Anesthetics. B. Muscle relaxants. C. Local Anesthetics. 5. Analgesics/Antirheumatics. A. Narcotic analgesics. B. Non-narcotic analgesics/non-steroidal antiinflammatory drugs. C. Antirheumatics. D. Drugs against gout. 6. Anticonvulsants. A. Hydantoins. B. Succinimides C. Oxazolidines. D. Barbiturates. E. Miscellaneous. 7. Antihistamines, antiallergic agents and drugs affecting autonomic functions. A. H1-Receptor antagonists. B. H2-Receptor antagonists. C. Xanthine derivatives. D. Beta-antagonists. E. Miscellaneous. 8. Antihypertensive agents. A. Adrenergic neuron blockers. B. Centrally-acting antihypertensive drugs. C. Peripherally-acting antihypertensive drugs. D. Diuretics E. Angiotensin-I converting enzyme inhibitors. 9. Antithrombotic agents and blood products. A. Anticoagulants. B. Platelet aggregation inhibitors. C. Thrombolytics. D. Blood expanders. E. Miscellaneous. 10. Antiarrhythmics/cardiovascular agents. A. Antiarrhythmics. B. Other cardiac agents. 11. Hormones and derivatives. A. Corticosteroids. B. Thyroid/antithyroid agents. C. Antidiabetic agents. D. Sex Hormones and antagonists. E. Miscellaneous. 12. Immunoregulators and vaccines. A. Microbial derivatives. B. Synthetic products. C. Biotechnology products. D. Vaccines. 13. Immunosuppressants and antineoplastic agents. A. Chemical immunosuppressants. B. Monoclonal antibodies. C. Antineoplastic agents. 14. Antimicrobial agents. A. Antibodies. B. Sulphonamides. C. Antibacterial chemotherapeutic agents. D. Antimycotics. E. Antituberculous agents. F. Antileprotic agents. G. Antiprotozoal agents. H. Antiviral agents. I. Miscellaneous. 15. Psychopharmacological agents. A. Neuroleptics. B. Hypnotics/sedatives/anxiolytics. C. Antidepressants. D. Psychostimulants. E. Antiparkinson drugs. F. Miscellaneous. 16. Miscellaneous drugs. A. Contrast media. B. Vitamins and derivatives. C. Drugs affecting lipid metabolism. Index.
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