The Childhood environment and adult disease
著者
書誌事項
The Childhood environment and adult disease
(Ciba Foundation symposium, 156)
Wiley, 1991
大学図書館所蔵 全10件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Based on the Symposium on the Childhood Environment and Adult Disease, held at the Ciba Foundation, London, 16-17 May 1990
Editors: Gregory R. Bock (organizer) and Julie Whelan
"A Wiley-Interscience publication."
Includes bibliographical references and index
内容説明・目次
内容説明
The Childhood Environment and Adult Disease Chairman: D.J.P. Barker 1991 A relationship between events in prenatal life or early childhood and subsequent disease, physical or mental, in adulthood has previously been difficult to pin down, and open to speculation rather than analysis. It is now possible in epidemiological studies to relate measurable aspects of neonatal health to measures of disease in adult life. This wide-ranging symposium is the first to draw together the various strands in this new research area. The links between early growth and the risk of high blood pressure, stroke and coronary heart disease in adult life are explored. Poor growth of babies is shown to be related to the inadequate growth and nutrition of mothers. Mediating factors being investigated include levels of blood cholesterol and clotting factors. The fetal response to intrauterine stress is being studied in a sheep model; other studies in primates are examining the relation between early nutrition (breast or formula feeding) and later cholesterol metabolism, with the possible disease implications.
Dietary manipulation studies in preterm babies are revealing the long-term effects of early nutrition on cardiovascular and neurodevelopmental measures. Other chapters consider the connections between early nutrition (including that of the mother and even the grandmother) and the immune system. Infections in childhood may have even longer-term effects, with evidence that the epidemiology of polio 40 years ago is being mirrored by that of motor neuron disease. Critical periods in the development of the brain and the visual system, when vulnerability to damage may be greatest, are analysed. The possible origin of schizophrenia in pathological processes in fetal and perinatal life is another instance where developmental events and adult disease (this time in the psychological arena) may be causally related. Finally, the consequences of adverse early experiences for adult psychosocial functioning are described in longitudinal studies in humans, and in studies on rhesus monkeys, in which the harmful effects of stress in infancy on adult behaviour can nevertheless be overcome by rearing by nurturant foster mothers.
Other Ciba Foundation Symposia: No 130 Molecular approaches to human polygenic disease Chairman: Sir David Weatherall 1987 ISBN 0 471 91096 1 No 149 Human genetic information: science, law and ethics Chairman: Sir Gustav Nossal 1990 ISBN 0 471 92624 8 No 152 The biology of nicotine dependence Chairman: L. L. Iversen 1990 ISBN 0 471 92688 4
目次
Partial table of contents: The Intrauterine Environment and Adult Cardiovascular Disease (D. Barker). Programming by Early Nutrition in Man (A. Lucas). Programming of Cholesterol Metabolism by Breast or Formula Feeding (G. Mott, et al.). Interactions Between Early Nutrition and the Immune System (R. Chandra). Childhood Infection and Adult Disease (C. Martyn). Critical Periods in Brain Development (J. Smart). Fetal Brain Development and Later Schizophrenia (R. Murray, et al.). Early Stress and Adult Emotional Reactivity in Rhesus Monkeys (S. Suomi). Childhood Experiences and Adult Psychosocial Functioning (M. Rutter). Index of Contributors. Subject Index.
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