The Importance of animal experimentation for safety and biomedical research
Author(s)
Bibliographic Information
The Importance of animal experimentation for safety and biomedical research
Kluwer Academic Publishers, c1990
- : U.S. : alk. paper
Available at 4 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Presents the proceedings of an international symposium organized in Strasbourg, Oct. 24-25, 1988
Includes bibliographical references
Description and Table of Contents
Description
Scientists are coming under increasing pressure from activist groups to stop animal experimentation, branded as cruel and unnecessary for improving human health. This attitude, however, stems from an unrealistic evaluation of the situation and distorted information about present scientific knowledge. There is no question that most medical progress - perhaps all, in fac- has been attained through knowledge derived initially from experiments in various animal species. There is practically no way of replacing animals in these investigations and so-called 'alternative methods' are in reality merely complementary. Tissue cultures, cell, microorganisms, enzymes, membranes, mathematical models - all are useful for preliminary screening tests and for testing hypotheses, but the complexity of a living organism is such that in vivo studies are essential before any test can responsibly be made in man. This book presents the proceedings of an international symposium organized in Strasbourg (October 24-25, 1988), with the aim of assessing present-day requirements as regards animal experimentation in research related to major medical and toxicological problems still awaiting solutions.
Table of Contents
The necessity of animal experimentation.- Ethical and Legal Aspects.- Animal experimentation defended.- The ethics of animal use in biomedicine.- Legal and political problems of animal experimentation, the 'Swiss battle'.- Experimentation and the law.- Experimentation on animals: animals as machines and animals as fetishes.- Recent Progress of Medicine Requiring the Use of Animals.- The role of animal experiments in pharmacological brain research.- Regeneration of the nervous system.- Endocrine glands, neuroendocrinology and animal experimentation.- Laboratory animals and cardiovascular pathology: means for better use.- The importance of animal models for hypertension research.- Animal experiments and recent progress in thrombosis research.- Models of human renal disease.- The necessity of animal experimentation in tumor immunology.- The use of animals in cancer chemotherapy.- The use of experimental animals in transplantation research.- Animal models for AIDS research.- The need for animal experimentation in drug and vaccine development against tropical diseases.- Use of Animals for Safety Reasons.- Toxicology: role of in vivo studies in establishing mcchanisms of toxicity.- Necessity of animal experiments for the safety evaluation and necessary consequences for public health.- The necessity of animal testing for safety evaluation and medical progress in reproductive biology and toxicology.- The need for animal experimentation in studying the carcinogenic risk of substances.- The Future of Animal Research.- Transgenic animals for human diseases and gene therapy.- Recent progress toward reducing the use of animal experimentation in biomedical research.- Animal use in drug research.
by "Nielsen BookData"