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v. 1 ISBN 9780849343933
内容説明
Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.
目次
VOLUME I: Free Flavins: Syntheses, Chemical and Physical Properties. Structure, Synthesis, and Physical Properties of Covalently-Bound Flavins and 6- and 8-Hydroxyflavins. Roseoflavin, Nekoflavin, and Schizoflavin. Syntheses and Properties of 5-Deazaflavins. The Photochemistry of Flavins. Flavin Metabolites. Medical Aspects of Vitamin B2. Biosynthesis of Flavins. Methods Used to Reversibly Resolve Flavoproteins into the Constituents Apoflavoproteins and Prosthetic Group. Flavoproteins in Medicine. Riboflavin-Binding Proteins. The Lumazine/Riboflavin Synthase Complex of Bacillus Subtilis. DNA Photolyase and the Role of Flavin in DNA Repair. Cellobiose Oxidoreductase. Riboflavin Kinase and FAD Synthetase. Mammalian Methylenetetrahydrofolate Reductase. 5,10-Methylenetetrahydrofolate Reductases: Iron-Sulfur-Zinc Flavoproteins of Two Acetogenic Clostridia. Redox Properties of Flavins and Flavoproteins.
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v. 2 ISBN 9780849343940
内容説明
Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.
目次
VOLUME II: Flavin-Dependent Monooxygenases with Special Reference to p-Hydroxybenzoate Hydroxylase (W.J.H. van Berkel and F. Muller). The Structure of p-Hydroxybenzoate Hydroxylase (H.A. Schreuder, J.M. van der Laan, W.G.J. Hol and J. Drenth). Phenol Hydroxylase (H.Y. Neujahr). The Multisubstrate FAD-Containing Monooxygenase (L.L. Poulsen). A Steroid Ketone Monooxygenase from Cylindrocarpon radicicola (M. Katagiri and E. Itagaki).The Mechanism of Bacterial Bioluminescence (J. Lee, I.B.C. Matheson, F. Muller, D.J. O'Kane, J. Vervoort and A.J.W.G. Visser). Flavocytochrome b2 (F. Lederer). L-Lactate Oxidase (S. Ghisla and V. Massey). Nitroreductases (C. Bryant and W.D. McElroy). Ferredoxin: NADP+ Oxidoreductase (G. Zanetti and A. Aliverti). Enoate Reductase (H. Simon). NADPH-Adrenodoxin Oxidoreductase (J. Nonaka, R. Miura and T. Yamano). Covalent Flavoproteins (K. Decker). Flavocytochrome c. (M.A. Cusanovich, T.E. Meyer and R.G. Bartsch). The Biochemical Properties and Structure of Trimethylamine Dehydrogenase (D.J. Steenkamp and F.S. Matthews). Role of the Covalent and Noncovalent Flavins in Sarcosine Oxidase (K. Kvalnes-Krick and M. Schuman-Jorns). Monoamine Oxidases (T.P. Singer). Electron-Transferring Flavoproteins (C. Thorpe).
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v. 3 ISBN 9780849343957
内容説明
Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.
目次
- VOLUME III: Pyridoxine-5-P Oxidase (F. Kwok and J.E. Churchich). Xanthine Oxidase, Xanthine Dehydrogenase and Aldehyde Oxidase (R. Hille). D- and L-Amino Acid Oxidases (B. Curti, S. Ronchi, and M.P. Simonetta). Methanol Oxidase (F. Muller, T.R. Hopkins, J. Lee, and P.I.H. Bastiaens). Lipoamide Dehydrogenase, Glutathione Reductase, Thioredoxin Reductase and Mercuric Ion Reductase - Family of Flavoenzyme Transhydrogenases (C.H. Williams, Jr.). The Refined Three-Dimensional Structure of Glutathione Reductase (P.A. Karplus and G.E. Schulz). Structure and Function of Succinate Dehydrogenase and Fumarate Reductase (B.A.C. Ackrell, M.K. Johnson, R.P. Gunsalus, and G. Cecchini). Three-Dimensional Structure of Medium-Chain Acyl-CoA Dehydrogenase (J.-J. P. Kim and J. Wu). Glutamate Synthase (M.A. Vanoni, B. Curti, and G. Zanetti). Assimilatory Nitrate Reductase (M.J. Barber and L.P. Solomonson). Biological Reduction and Formation of Sulfate
- The Role of APS Reductase, a FAD(Iron-Sulfur)-Containing Protein (J. Lampreia, I. Moura, A.V. Xavier, J. Le Gall, H.D. Peck, Jr., and J.J.G. Moura). The Stereochemistry of the Prosthetic Groups of Flavoproteins (E.F. Pai). Structure and Mechanism of Spinach Glycolate Oxidase (Y. Lindqvist). General Properties of Flavodoxins (S.G. Mayhew and G. Tollin). Structure and Redox Properties of Clostridial Flavodoxin (M.L. Ludwig and C.L. Luschinsky). Biochemistry and Molecular Biology of Bacterial Bioluminescence (T.O. Baldwin and M.M. Ziegler). Acetolactate Synthase (J.V. Schloss). Phthalate Dioxygenase Reductase and Related Flavin-Iron-Sulfur-Containing Electron Transferases (C.I. Batie, D.P. Ballou, and C.C. Correll). Nuclear Magnetic Resonance Studies on Flavoproteins (F. Muller). Acyl-Coenzyme A Dehydrogenases (P. Engel).
CONTRIBUTORS:
Dr. Adelbert Bacher. Jane L. Chastain. Dr. Joan E. Clark. Dr. Raffaele De Francesco. Dr. Paul F. Heelis. Wendy S.A. Innis-Whitehouse. Dr. Sabu Kasai. Dr. R. Luise Krauth-Siegel. Dr. Dale E. Edmondson. Dr. Marilyn Schuman-Jorns. Dr. Kunio Matsui. Dr. Donald B. McCormick. Dr. R.Heiner Schirmer. Dr. Fumio Yoneda. Dr. Alfred H. Merrill, Jr. Dr. D.V. DerVartanian. Dr. Bruno Kokel. Dr. Rudolf Ladenstein. Dr. Lars G. Ljungdahl. Dr. Rowena G. Matthews. Dr. Fraser F. Morpeth. Dr. Eun Young Park. Dr. Richard S. Rivlin. Dr. Marian T. Stankovich. Dr. Willem J.H. van Berkel.
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