Bibliographic Information

Selective fluorination in organic and bioorganic chemistry

John T. Welch, editor

(ACS symposium series, 456)

American Chemical Society, 1991

  • : alk paper

Available at  / 12 libraries

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Note

"Developed from a symposium sponsored by the Division of Fluorine Chemistry at the 199th National Meeting of the American Chemical Society, Boston, Massachusetts, April 22-27, 1990"

Includes bibliographical references and indexes

Description and Table of Contents

Description

This 14-chapter volume addresses theoretical and synthetic problems, as well as applications of selective fluorination to biological systems. Many of the contributors are noted authorities in the field. It will serve as an excellent reference for fluorine chemists, biochemists, medicinal and organic chemists.

Table of Contents

  • Tentative
  • Effects of Selective Fluorination on Reactivity in Organic and Bioorganic Chemistry: Introduction
  • The Effect of Fluorination on Polyacetylene and the Role of Internal Hydrogen Bonds to Fluorine: Molecular Orbital Models
  • Systematics and Surprises in Bond Energies of Fluorinated Reactive Intermediates
  • New Oxidants Containing the O-F Moiety and Some of their Uses in Organic Chemistry
  • Perfluorinated-Alkenes and -Dienes in a Diverse Chemistry
  • Perfluoro-Enolate Chemistry: Selective Generation and Unique Reactions of Ketone F-Enolates
  • New Approaches to *a-Fluoro and *a,*a-Difluoro Functionalized Esters
  • Terminal Fluoroolefins: Synthesis and Applications to Mechanism-Based Enzyme Inhibition
  • Fluorine-Substituted Neuroactive Amines
  • Aldolases in Synthesis of Fluorosugars
  • Renin Inhibitors: Fluorine-Containing, Transition-State Analogue Inserts
  • The Effect of Fluorine Atom on Stereocontrolled Synthesis with Chemical or Microbial Methods
  • Fluoroolefin Dipeptide Isosteres
  • The Influence of Fluoro Substituents on the Reactivity of Carboxylic Acids, Amides, and Peptides in Enzyme-Catalyzed Reactions

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