Molecular biology and differentiation of megakaryocytes : proceedings of the Third International Conference on Megakaryocytes: Megakaryocytes: Cellular and Molecular Biology, held at Conseil Régional de Bourgogne, Dijon, France, July 23-27, 1989

Bibliographic Information

Molecular biology and differentiation of megakaryocytes : proceedings of the Third International Conference on Megakaryocytes: Megakaryocytes: Cellular and Molecular Biology, held at Conseil Régional de Bourgogne, Dijon, France, July 23-27, 1989

editors, Janine Breton-Gorius ... [et al.]

(Progress in clinical and biological research, v. 356)

Wiley-Liss, c1990

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Includes index

Description and Table of Contents

Description

This work assembles the contributions of authorities from many areas of cell biology in order to provide a critical account of recent developments in the field that have led to the considerable expansion of megakaryocyte research. Technological advances that have opened up new vistas in the study of megakaryocytes - defining their roles in platelet production, hematopoietic regulation, and a variety of platelet and vascular disorders - are also covered. Divided into sections on megakaryocyte maturation, regulation and pathology, the book also features discussion summaries that clarify and expand the material covered in the individual chapters.

Table of Contents

  • Partial table of contents:
  • MATURATION OF MEGAKARYOCYTES
  • Delivery of Platelets from Megakaryocytes (J. White)
  • Circulating Megakaryocytes and Platelet Production in the Lungs (R. Levine, et al.)
  • Molecular Biology of the Megakaryocyte-Specific Gene Platelet Factor 4 (M. Poncz)
  • Proteoglycans in Megakaryocyte Development (B. Schick)
  • The Origin of Platelet -Granule Proteins (P. Handagama, et al.)
  • REGULATION OF MEGAKARYOCYTOPOIESIS
  • The Regulatory Control of Hemopoietic Populations (D. Metcalf)
  • Studies on Paracrine Regulation of Murine Megakaryocytopoiesis (N. Williams, et al.)
  • Control and Implications of Polyploidization in Human Megakaryocytes (E. Mazur)
  • Growth and Differentiation of Two Human Megakaryoblastic Cell Lines: CMK and UT-7 (Y. Miura, et al.)
  • PATHOLOGY OF MEGAKARYOCYTOPOIESIS
  • Retroviral Antigen Expression on Megakaryocytes and Platelets: Possible Implications in the Pathogenesis of Thrombocytopenia (G. Grau & P. Lambert)
  • Flow Cytometric Analysis of Megakaryocytes (Mks) from Patients with Platelet Disorders (R. Conklin, et al.)
  • Inherited Disorders of Platelets and Megakaryocytes (A. Nurden, et al.)
  • Index.

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