Basic and applied mutagenesis : with special reference to agricultural chemicals in developing countries
Author(s)
Bibliographic Information
Basic and applied mutagenesis : with special reference to agricultural chemicals in developing countries
(Basic life sciences, v. 34)
Plenum Press, c1985
Available at 2 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
"Based on a Symposium on Agricultural Genotoxicity in Developing Countries, held October 31-November 5, 1982, in Islamabad, Pakistan"--T.p. verso
Includes bibliographies and indexes
Description and Table of Contents
Description
The aim of the editors of this volume is to use basic and ap- plied studies in the field of mutagenesis to approach a problem of especial concern. The problem is that of the usage of toxic chemi- cals, particularly agricultural chemicals, in ever-increasing quan- tities in those parts of the world that feed the most people. Agri- cultural chemicals that are in use in Pakistan are emphasized here. These are the same chemicals that are in use throughout the develop- ing world, although the quantities of the different types that are used may vary from country to country, and from region to region within countries. A number of these chemicals can no longer be sold in Europe or in the United States, and it is often difficult to iden- tify a scientific reason as to why they are sold at all. It is ironic that toxic chemicals are used as a humanitarian device to rid the world of Pestilence and Famine -- two of the Horsemen of the Apocalypse. If we do not wish poisonous chemicals to become the fifth Horseman of the Apocalypse, then we must begin now to identify and regulate the large-scale usage of toxic sub- stances everywhere.
Table of Contents
I. Introduction.- Welcoming Address.- Inaugural Address.- Toxins in the Human Food System.- II. Risks to Human Health Induced by Pesticides.- General Human Health Risks Associated with the Use of Chemicals.- Water Contamination and Environmental Mutagens.- Problems Associated with the Use of Chemicals by Agricultural Workers.- Mechanism of Contamination from Agricultural Chemicals in Mammals.- Mycotoxins as Carcinogens.- III. Basic Studies Related to Mutagenesis and Carcinogenesis.- Cytotoxicity as a Mechanism of Carcinogenesis.- Mutagenesis-Enhancement by Plasmids in Mutagenesis Tester Strains.- Situation-Dependent Repair of DNA Damage in Yeast.- A Possible Role for Deoxyribonucleotide Pool Imbalances in Carcinogenesis.- Polysubstrate Monooxygenases in Drosophila, Mammals and Man.- IV. Mutagenic, Teratogenic, and Predictive Carcinogenic Studies of Pesticides.- Evaluation of the Genotoxic Potential of Certain Pesticides Used in Pakistan.- Mutagen Testing of Agricultural Chemicals with Yeast.- Plant Genetic Assays and their Use in Studies on Environmental Mutagenesis in Developing Countries.- Aneuploidy Induced by Agricultural Pesticides: Where Do We Stand?.- The Science of Teratology in a Regulatory Setting.- V. Appendix I - Protocols.- Mutagen Testing with Yeast.- Mutagen Testing with Maize.- Mutagen Testing with the Soybean Assay.- The Micronucleus Test on Exfoliated Human Cells.- Mutagenicity Testing with Drosophila melanogaster.- A FORTRAN Program for the Construction of Selby-Olson Tables.- VI. Appendix Psticides Registered in Pakistan.- Agricultural Chemicals Registered for Sale in Pakistan.- Author Index.- Chemical Index.
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