Recent advances in insulin action and its disorders : proceedings of the International Symposium on Insulin Action and Its Disorders, Shiga, 16 May 1990
著者
書誌事項
Recent advances in insulin action and its disorders : proceedings of the International Symposium on Insulin Action and Its Disorders, Shiga, 16 May 1990
（International congress series, no. 930）
Excerpta Medica , Sole distributors for the USA and Canada, Elsevier Science Pub. Co., 1991
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注記
Includes index
内容説明・目次
内容説明
Remarkable advances have been made in the field of insulin action with the aid of gene analysis techniques, which enable the clarification of the mechanism of the insulin receptor diseases and the structure - function relationship in glucose transporters. The book summarizes these recent advances in the field of insulin action. The volume also discusses insulin binding and action of insulin analogues, insulin receptor diseases, the substrates of insulin receptor kinase, abnormal insulin action in NIDDM and the mechanism of glucose transport, thus integrating the recent knowledge of insulin action from insulin to glucose transport. This proceedings volume is therefore an excellent review on recent advances in the research in insulin action and its disorders.
目次
Insulin structure and insulin action. Bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake (K. Drejer, U. Ribel, V. Kruse, A.R. Sorensen, I. Jensen and S. Gammeltoft). Mutant insulin receptors. Insulin resistance by unprocessed insulin proreceptors due to point mutation at the cleavage site (M. Kobayashi, T. Sasaoka, M. Sugibayashi and Y. Shigeta). Genetic defect of T-subunit of insulin receptors (H. Makino, M. Taira, F. Shimada, N. Hashimoto, Y. Shimada, O. Nozaki and S. Yoshida). Signal transduction in insulin action. Evidence for insulin-dependent activation of serine kinase activity via tyrosine kinase activity of insulin receptors (Y. Tashiro-Hashimoto, R. Yamamoto-Honda, K. Momomura, K. Tobe, Y. Akanuma and M. Kasuga). The structure and regulation of the insulin-activated S6 (SER/THR) protein kinases: Signalling intermediates in insulin action (J. Avruch, D.J. Price, P. Banerjee, M.F. Ahmad, J.R. Grove, N. Mukhopadhyay, A. Balasubramanyam and J.M. Kyriakis). Insulin action in NIDDM and ageing. Insulin action and insulin resistance in non-insulin dependent diabetes mellitus (J.M. Olefsky). Changes in insulin action with ageing in rats (H. Kuzuya, H. Nishimura, S. Kono, A. Kosaki, G. Inoue, M. Okamoto and M. Okamoto). Mechanism of glucose transport. Glucose transporter -structure and function (Y. Oka and T. Asano). Insulin activated glucose transport, mechanistic questions (P.F. Pilch). Index of Authors.
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