New trends in haemostasis : coagulation proteins, endothelium, and tissue factors
著者
書誌事項
New trends in haemostasis : coagulation proteins, endothelium, and tissue factors
（Veröffentlichungen aus der Geomedizinischen Forchungsstelle der Heidelberger Akademie der Wissenchaften）（Supplement zu den Sitzungsberichten der Mathematisch-Naturwissenschaftlichen Klasse, Jahrg. 1990）
Springer-Verlag, c1990
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注記
Based on a symposium held in 1990 at the Heidelberg Academy for the Humanities and Sciences
内容説明・目次
内容説明
To give an update in the field of haemostasis scientists and
clinicians fromoverseas and European countries met to dis-
cuss the new trends in pathophysiology and clinical impli-
cations. This book is devoted to the interactions of endo-
thelial functions, tissue factors, coagulation inhibitors
and haemostasis as well as detection and prophylaxis of
thromboembolism. Data are presented of significant new re-
search work on molecular and clinical approaches to diseases
in haemostasis.
目次
- Endothelial Functions and Haemostasis.- Structure, Shape and Function of Glycosaminoglycans.- Structure and Metabolism of Glycosaminoglycans.- Fibrin Polymerization and Its Role in Regulating Haemostasis.- Function of von Willebrand Factor in Plasma.- Biosynthesis and Assembly of the Factor VIII - von Willebrand Factor Complex.- Modulation of Endothelial Cell Function by Hypoxia: Perturbation of Barrier and Anticoagulant Function and Induction of a Novel Procoagulant Activity.- Tissue Factors and Endothelium.- Platelet Adhesion
- A Concerted Action of Hemodynamic and Biochemical Processes.- Modulation of Endothelial Functions by Advanced Glycosylation End Products.- Procogulant Activities of Leukocytes.- Cytokine Induced Stimulation of Endothelial Cells in Vitro.- Anti-Platelet Treatment of Metastasis.- The Molecular Anatomy of Vitronectin as Extracellular Regulator Protein: Multifunctional Properties of the Heparin-Binding Domain.- Mode of Action of Annexin V (Vascular Anticoagulant Alpha), A Protein Synthesized by the Vessel Wall.- Coagulation Inhibitors and Haemostasis.- Clinical Pharmacologal Profile of Low Molecular Weight Heparins.- Anticoagulant Actions of Sulphated Polysaccharides.- Development of Synthetic Proteinase Inhibitors as Anticoagulant Agents.- Antithrombin and Its Deficiency States.- "New" Coagulation Inhibitors.- Biological Function of Vitamin K Antagonists.- Plasminogen Activator Inhibitors: Biological Effects.- Fibrin-Specific Clot Lysis with Single Chain Urokinase-Type Plasminogen Activator (scu-PA).- Antibody - Mediated Thrombolysis: Promise and Problems.- Thromboembolism: Detection and Prophylaxis.- Causation and Prevention of Coronary Thrombosis: Present Situation.- Non-Invasiva Diagnostic Techniques in Deep Vein Thrombosis.- Evaluation of the Bleeding Effects of Antithrombotic Drugs.- List of Participants.- List of Sponsors.
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