Comparative aspects of neuropeptide function

著者

書誌事項

Comparative aspects of neuropeptide function

edited by Ernst Florey and George B. Stefano

(Studies in neuroscience, no. 11)

Manchester University Press , Distributed exclusively in the USA and Canada by St. Martin's Press, c1990

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注記

Based on a meeting held in Konstanz, Germany in 1989 and sponsored by the Deutsche Forschungsgemeinschaft and others

Includes index

内容説明・目次

内容説明

This is collection of papers from an International Symposium on neuropeptide research. The papers cover different aspects of the subject, from that of molecular genetics and the cellular level to that of the interaction of entire organisms. The organismic approach is essential for the understanding of the role of neuropeptides in the interactions between the nervous system and "immunocytes". In its course the symposium raised questions about the release and the control of the release of "classic" transmitters and neuropeptides. The site of this release and the release of control agents for "classic" transmitters and neuropeptides was also discussed. Transmitter receptor synthesis and the incorporation into membranes was also considered. The role of neuropeptides in haemocyte production and "stress" was discussed as were the methods of experimentation needed to explore the role and release control of neuropeptides from haematocytes attached to endothelium. Finally the role of haematocytes as floating synaptosomes was considered. The chapters included in this book discuss these topics and attend to some of the questions raised by the Symposium. The chapters are grouped in sections for taxonomis reasons: because of their natural, evolutionary relationship, molluscs, or arthropods, or mammals, have special features which make comparisons within the taxonomic group easier than comparison between groups, although cross-comparisons are possible. This book does not cover the entire field of neuropeptide research, but its strength lies in its interdisciplinary approach.

目次

  • Part 1 General aspects: neurosecretion - the beginnings
  • stereo-specificity as a determining force stabilizing families of signal molecules within the context of evolution. Part 2 Molluscan studies: peptide pharmacology on giant neurons of a giant snail (Achatina fulica Ferrussac)
  • effects of the catch-relaxing peptide on identified neurons of the snail Helix pomatia L.
  • distinct responses to opiate peptides and FNRFamide on B-neurons of the Aplysia cerebral ganglia
  • opioid peptides, nociception and analgesia in molluscs
  • neuropeptides isolated from Mytilus edulis (Bivalvia) and Fusinus ferrugineus (Prosobranchia)
  • neuropeptide modulation of central neuronal networks and peripheral targets in terrestrial slugs
  • peptidergic neurons in the aging molluscan brain
  • neuronal control of male reproductive function in pulmonate and opisthobranch gastropods
  • evolutionary aspects of morphology and function of peptidergic systems, with particular reference to the pond snail Lymnaea stagnalis. Part 3 Arthropod studies: peptidergic modulation of synaptic transmission in locust skeletal muscle
  • the molecular basis for steroid regulation of eclosion hormone action in the tobacco hornworm, Manduca sexta
  • neurosecretory ending in the pericardial organs of the shore crab, Carcinus maenus L. and their identification by neuropeptide-immunochemistry, H.Dircksen
  • biological effects of crustacean cardioactive peptide (CCAP), a putative neurohormone/neurotransmitter from crustacean pericardian organs
  • neuropeptides and neurotransmitters in the X-organ sinus gland complex, an important neuroendocrine function integration centre in the eyestalk of Crustacea
  • neurohormone D - function and inactivation
  • involvement of neuropeptides in insect water regulation - the African locust model - comparison with other insects and vertebrate systems. Part 4 Euchiuroid neuropeptides: structures and actions of neuropeptides isolated from an Echiuroid worm, Urechis unicinctus. Part 5 Vertebrate studies: purines - neuromodulators and metabolic regulators of bioreactivity in the nervous system
  • a common mechanism of excitation of the area postrema neurons by several neuropeptides, hormones and monoamines
  • regulation by neuropeptides of amino acid transmitter release in mammalian brain and retina
  • comparative aspects of the submicroscopical immunocytochemical localization of neuropeptides
  • the interaction of posterior pituitary neuropeptides with dopamine in experimental drug addiction - the relevance of rodent models
  • Part 6 Neuro-immunology: neuropeptides and neuropeptide receptors in the immune system
  • opioid neuropeptides in invertebrate hemolymphs
  • comparative aspects of the response of human and immunocytes to stimulation by opioid neuropeptides
  • modulation of leukocyte migration by alpha melanocyte stimulating hormone.

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