Bibliographic Information

Radiation injury to the nervous system

editors, Philip H. Gutin, Steven A. Leibel, Glenn E. Sheline

Raven Press, c1991

Available at  / 10 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This presents findings on nervous system injuries resulting from radiation therapy and offers guidelines on diagnostic imaging and treatment of these injuries. It also explores the prospects for radioprotection of the nervous system. Experts examine the response of normal tissue to radiation and the influence of fractionation and dose rate on tissue tolerance and present experimental studies and clinical observations on radiation-induced central nervous system injury. Included are reports on injury resulting from commonly used and state-of-the-art radiation therapies.

Table of Contents

  • Part 1 Response of normal tissue to ionizing radiation: cellular and molecular targets in normal tissue radiation injury
  • biochemical response of normal tissues to ionizing radiation
  • early and late effects of radiation on normal tissues
  • influence of fractionation on normal tissue tolerance
  • influence of dose rate on normal tissue tolerance. Part 2 Tolerance of the nervous system to ionizing radiation - experimental results: central nervous system radiation injury in small and large animal models
  • experimental central nervous system injury from fast neutrons and from implanted isotopes
  • the pathology of central nervous system radiation injury. Part 3 Tolerance of the nervous system to ionzing radiation - clinical experience: diagnostic imaging of central nervous system radiation injury
  • tolerance of the brain and spinal cord to conventional irradiation
  • factors affecting radiation injury after interstitial brachytherapy for brain tumors
  • treatment of radiation necrosis of the brain
  • tolerance of the visual apparatus to conventional therapeutic irradiation
  • radiation and the hypothalamic-pituitary axis
  • changes in intellect associated with cranial radiation therapy
  • injury to the central nervous system after high LET radiation
  • drug/radiation interactions and central nervous system injury
  • radiation injury to peripheral and cranial nerves. Part 4 Tolerance of the nervous system to ionizing radiation - related issues: the effects of heat on the nervous system
  • prospects for radioprotection of the nervous system
  • radiation-induced tumors of the nervous system.

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