書誌事項

Enzymes in carbohydrate synthesis

Mark D. Bednarski, editor, Ethan S. Simon, editor

(ACS symposium series, 466)

American Chemical Society, 1991

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注記

"Developed from a symposium sponsored by the Division of Carbohydrate Chemistry at the 199th National Meeting of the American Chemical Society, Boston, Massachusetts, April 22-27, 1990."

Includes bibliographical references and indexes

内容説明・目次

内容説明

Not only assessing the past, present, and future uses of enzymes to synthesize carbohydrates, this volume also illustrates the significance of carbohydrate chemistry and describes how the combination and use of modern enzyme chemistry can advance exploration in the field. Details research at the interface of chemistry and biology for carbohydrate chemistry by demonstrating how to integrate chemical reactions and biological techniques that can be used to synthesize complex bioactive monosaccharides, oligosaccarides, and glycoconjugates. Of particular interest are chapters by George Whitesides and Chi-Huey Wong covering the use of enzymes in monosaccharide synthesis, and Hindsgaul, Thiem, Nilsson, and Whitesides describing the use of activated sugar nucleosides and glycosyltransferases in the synthesis of oligosaccharides and polysaccharides.

目次

  • Enzymes as Catalysts in Carbohydrate Synthesis
  • Microbial Aldolases in Carbohydrate Synthesis
  • Use of Glycosyltransferases in Synthesis of Unnatural Oligosaccharide Analogs
  • Use of Glycosidases and Glycosyltransferases in the Synthesis of Complex Oligosaccharides and Their Glycosides
  • Glycosylation by Use of Glycohydrolases and Glycosyltransferases in Preparative Scale
  • Use of Glycosyltransferases for Drug Modification
  • Some Aspects of Enzymic Synthesis of Oligosaccharides Employing Acceptor Saccharides Attached to Polymer Carriers
  • Galactose Olidase: Selected Properties and Synthetic Application
  • Industrial Application of Adenosine 5'-Triphosphate Regeneration to Synthesis of Sugar Phosphates

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