New strategies in parasitology : proceedings of an international symposium, sponsored by Glaxo Research, Brocket Hall, Hertfordshire, 22-25 April 1989

著者

    • McAdam, Keith P. W. J.

書誌事項

New strategies in parasitology : proceedings of an international symposium, sponsored by Glaxo Research, Brocket Hall, Hertfordshire, 22-25 April 1989

edited by Keith P.W.J. McAdam

(Frontiers of infectious diseases)

Churchill Livingstone, 1989

1st ed

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book provides the record of a meeting in Brocket Hall, Hertfordshire, England between 22-25th April 1989. The meeting was the second in an ongoing series on "Frontiers of Infectious Diseases", this year devoted to new stategies in parasitology. A group of 40 leading investigators, from both Europe and the USA, met for three days to summarise recent advances in their areas of research and to speculate about the future directions in the subject of parasitology. The topics chosen for inclusion in the parasitology meeting were selected as being areas of special interest and recent advances. Several presentations at the meeting discussed vaccine development. Castode vaccines have been developed for veterinary practice and the empirical approach has been highly successful within a short time frame. On the other hand a systematic logical approach is advocated for human parasites and this has inevitably yielded slow progress but great understanding of the mechanisms underlying host/parasite interactions. Animal models have been developed including a mouse model for cerebral malaria. The advent of the AIDS epidemic has given fresh relevance to parasitology and position papers presented current research on these oppportunites parasite infections. Several previosly rare organisms have become everyday words including pneumocystis and cryptosporidium. Animal models have been developed and `in vitro' life cycles established. In this rapidly changing field pneumocystis has become the commonest opportunistic infection in AIDS patients and is now regarded as a fungus; cryptosporidium is one of the commonest causes of diarrhoea in patients with HIV infection. Recent advances in immunology, molecular biology and pharmacology still need to be turned into effective products for the treatment and prevention of diseases that effects a large proportion of the population of the world. The strategies for the implementation of health were discussed. This meeting highlighted the developemnts in the science and clinical practice of parasitology.

目次

  • A success in veterinary parasitology - oestode vaccines, Mike D. Rikard. Part 1 Malaria: antigenic diversity of the asexual blood stages of plasmodium falciparum, Robin Anders
  • from sporozoite to liver stages - the saga of the irradiated sporozoite vaccine, Pierre Druile
  • cerebral malaria, Paul Lambert and E.Grau
  • the role of the plasma membrane in the response of parasites to stress, Carlos Gitler. Part 2 Trypanosomes: African trypanosomes - an elusive target, David Barry
  • the membrane attachment of the variant surface glycoprotein coat of trypanosama brucei, Michael Ferguson. Part 3 Leishmaniasis: CD4 + T cell subsets in marine leishmaniasis, Richard Locksley
  • T-cell responses and immunity to experimental infection with Leshmania major, Jacques Louis. Part 4 Schistosomiasis: idiotype networks in schistosomiasis, Dan Colley
  • immunity and morbidity in human schistosomiasis, Antony Butterworth
  • selective primary health care and parasitic diseases, Ken Warren. Part 5 Aids associated parasitic diseased: cyptosporidiosis, William Current
  • pneumocystis carinii - advances in biology, prophylaxis and treatment, Walter Hughes
  • rationally modulating the immune response, Jonathan Rothband.

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