Occupational toxicants : critical data evaluation for MAK values and classification of carcinogens
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Occupational toxicants : critical data evaluation for MAK values and classification of carcinogens
Wiley-VCH, c1991-
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At head of title: DFG, Deutsche Forschungsgemeinschaft
Vol. 9,10,12,14,16: ed. by Hermut Greim ; translation and layout, A.E. Wild and J. Handwerker-Sharman
Description and Table of Contents
- Volume
-
v. 1 : gw ISBN 9783527270194
Description
The Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area was called into being by the German Science Foundation in 1955. Its mandate was to continue the development begun by German toxicologists in the last century and to establish a scientific basis for the protection of workers from the adverse effects of toxic chemicals, making recommendations for the establishment of "MAK" values (maximimum concentrations at the workplace) and the classification of carcinogenic substances. Since then the scope of the Commission's activities has been extended, and its recommendations are published annually in the form of evaluation documents. The present volume is the first in a series of English translations of these evaluation documents, including a selection of the Commission's work in the establishment of "MAK" values in the last two years.
Table of Contents
- Part 1 General papers: carcinogenic medicines
- germ cell mutagens
- limitation of exposure peaks
- nitrosation of volatile amines at the workplace
- passive smoking at work. Part 2 Single substances, substance classes and complex mixtures: 1-chloro-1,1-diffluoroethane
- chlorotrifluoromethane
- 1,2-dichlorobenzene
- 1,3-dichlorobenzene
- 1,2-dichloromethoxyethane
- 1,3-dichloro-2-propanol
- diesel engine emissions
- dimethyl ether
- dimethyl hydrogen phosphite
- dimethylsulfamoyl chloride
- dinitrobenzene (all isomers)
- hydrazine
- limonene
- 2-methoxy-1-propanol
- 2-methoxypropyl-1-acetate
- n-methylene-bis(2-chloroethyl)amine
- methyl2-cyanoacrylate and ethyl 2-cyanoacrylate
- 4,4'-methylene-bis(n,n-dimethylaniline)
- 4-nitrobiphenyl
- n-nitrosamines
- perchloromethylmercaptan
- 1,1,2,2-tetrachloro-1,2-difluoroethane
- thiourea
- tri-n-butyltin compounds
- trichlorofluoromethane
- 2,2,4-trimethylpentane
- 2,4,6-trinitrotoluene
- 4-vinyl-1,2-cyclohexenediepoxide.
- Volume
-
v. 2 : gw ISBN 9783527270224
Description
English translation of the "Toxikolisch-arbeitmedizinischen Begrundungen von MAK Werten", showing which observations, experience and considerations determined the established MAK value. The text is intended for toxicologists, environmental chemists, food chemists and ecologists.
Table of Contents
- Part 1 Dusts: general threshold limit value for dust
- dust definitions and guidelines
- fumes definitions and guidelines
- aluminium
- asbestos
- calcium sulphate
- graphite
- iron oxides
- magnesium oxide
- polyvinyl chloride
- silica, amorphous
- talc (without asbestos fibres)
- titanium dioxide. Part 2 Metal-working fluid components: list of metal-working fluid components
- 1,2 benzisothiazol-3(2H)-one
- 1H-benzotriazole
- benzyl alcohol mono(poly)hemiformal
- bromo-2-nitro-1,3-propanediol
- p-chloro-m-cresol
- dibenzyl disulphide
- 2-hydroxymethyl-2-nitro-1,3-propanediol
- methyl-1H-benzotriazole
- o-phenylphenol and sodium o-phenylphenol
- tetrahydrobenzotriazole
- triphenyl phosphate
- N,N',N"-tris(beta-hydroxyethyl)-hexahydro-1,3,5-triazin(THT).
- Volume
-
v. 3 : gw ISBN 9783527270231
Description
The methods in this book emphasize the work of the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area into the specification and justification of maximum permissible concentrations of hazardous substances in the work area. In addition, they represent the methodological spectrum available today for the biological monitoring of occupationally exposed persons.
Table of Contents
- Acetaldehyde
- acrylamide
- beryllium and its compounds
- o-chloroaniline
- m-chloroaniline
- p-chloroaniline
- chlorodifluoromethan
- chloroethane
- chloroparaffins
- chromium and its compounds
- cobalt compounds
- 3,3'-diaminobenzidine
- 1,2-dichloroethane
- n,n-dimethylaniline
- dimethyl sulfoxide
- formaldehyde
- lithium hydride
- methyl methacrylate
- nitric acid
- 2-nitropropane
- organic peroxides
- pentachlorophenol
- tetrachloroethylene
- tetraethyl silicate
- o-toluidin and o-toluidinehydrochloride
- p-toluidine
- trichlorobenzene
- 1,1,2-trichloro-1,2,2-trifluoroethane.
- Volume
-
v. 4 : gw ISBN 9783527270255
Description
The methods in this book emphasize the work of the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area into the specification and justification of maximum permissible concentrations of hazardous substances in the work area. In addition, they represent the methodological spectrum available today for the biological monitoring of occupationally exposed persons.
Table of Contents
- Amitrol
- auramine, auramine base
- bis(beta-chloroethyl)sulfide
- 1,4-butane sultone and 2,4-butane sultone
- 1-n-butyl glycidyl ether and 1-tert-butyl glycidil ether
- epsilon-caprolactam
- carbon monoxide
- 3-chloro-2-methylpropene
- o-chloronitrobenzene
- m-chloronitrobenzene
- p-chloronitrobenzene
- p-chloronitrobenzene
- p-cresidine
- 1,4-dichlorobenzene
- dichloromethane
- 2,4-dichlorophenoxyacetic acid
- dichlorvos
- dimethl sulfate
- ethylene glycol
- glycidyl trimethylammonium chloride
- n-hexane
- hexane
- maleic anhydride
- 2-nitro-4-aminophenol
- 2-nitro-p-phenylenediamine
- phenyl glycidil ether
- 1,3-propane sultone
- tetranitromethane
- 4,4'-thiodianiline
- 2,4,5-trimethylaniline and its hydrochloride
- 1,3,5-trimethylbenzene
- vanadium pentoxide
- wood dust.
- Volume
-
v. 5 : gw ISBN 9783527270309
Description
Describes the data base which determines the level of a MAK value (maximum concentration value in the workplace) and gives a summary of the relevant international literature. The accumulated expertise of the Commission's toxicologists and occupational physicians makes the reviews not just accounts of the published data but also critical evaluation documents. Each evaluation document includes sections about toxic effects and modes of action, effects in humans, effects on animals, genotoxicity and carcinogenicity, and manifesto.
Table of Contents
- 3-amino-9-ethylcarbazole
- n-butyl acrylate
- 1,2-butylene oxide
- cadmium and its compounds
- calcium cyanamide
- 2-chloroethanol
- chlorofluoromethane
- n-chloroformylmorpholine
- alpha-chlorohydrin
- 3,3'-dichlorobenzidine
- dichlorodifluoromethane
- dichlorofluoromethane
- dicyclopentadiene
- 1,1-difluoroethylene
- 3,3'-dimethoxybenzidine
- 3,3'-dimethylbenzidine
- disulfiram
- ethylene oxide
- alpha-hexachlorocyclohexane and beta-hexachlorocyclohexane
- 2-isopropoxyethanol
- 1-methoxy-2-propanol
- 1-methoxypropyl-2-acetate
- 1,2-propylene oxide
- vinyl acetate
- vinyl chloride
- n-vinyl-2-pyrrolidone
- xylene (all isomers)
- metal-working fluid components
- 1,3-bis(hydroxymethyl)urea
- boric acid
- 5-chloro-2-methyl-2,3-dihydroisothiazol-3-one and 2-methyl-2,3-dihydroisothiazol-3-one
- 2,6-di-tert-butylphenol
- 2-ethyl-1,3-hexanediol
- hexamethylenetetramine
- 1-hydroxyethyl-2-heptadecenyl-imidazoline.
- Volume
-
v. 6 : gw ISBN 9783527270316
Description
This text provides critical data evaluation for MAK values and classification of carcinogens.
Table of Contents
- Ammonia
- Aniline
- Bromotrifluoromethane
- 2-Butoxyethanol
- 2-Butoxyethyl acetate
- Chlordimeform
- -Chlorinated Toluenes
- Chloropicrin
- Chlorothalonil
- 4-Chloro-o-toluidine and its hydrochloride
- 5-Chloro-o-toluidine
- 2,4-Diaminoanisole and 2,4-Diaminoanisole sulfate
- Dichloroacetylene
- Dinitrotoluenes (mixtures of isomers)
- Dipropylene glycol monomethyl ether
- 2-Ethoxyethanol
- 2-Ethoxyethyl acetate
- Ethyl acrylate
- Hydrogen chloride
- 2-Methoxyethanol
- 2-Methoxyethyl acetate
- Methyl acrylate
- N-Methylaniline
- 5-Nitro-o-toluidine
- 4,4-Oxydianiline
- m-Phenylenediamine
- o-Phenylenediamine
- p-Phenylenediamine
- Toluene-2,4-diamine
- Authors of Documents in Volume 6
- Index.
- Volume
-
v. 7 : gw ISBN 9783527270378
Description
This volume provides critical data evaluation for MAK values and classification of carcinogens. Detailed information is given on their toxic effects and modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity.
Table of Contents
- Acetone
- cadmium
- chlorinated paraffins
- chromium (VI) compounds
- dimethylformamide
- diethylene glycol monobutyl ether
- dimethylamine
- di-n-octyltin compounds
- ethyl bomide
- furfuryl alcohol
- gluraraldehyde
- isoflurane
- methylamine
- methyl bromide/chloride/iodide
- 2-nitrotoluene
- peracetic acid
- phthalic acid
- toluene
- phthalic anhydride
- tribomomethane. (Part contents).
- Volume
-
v. 8 : gw ISBN 9783527270385
Table of Contents
Dimethylformamide. Glutaraldehyde. 4,4'-Methylene Diphenyl Isocyanate (MDI) and "Polymeric MDI" (PMDI). 2-Nitrotoluene. Vinylidene Chloride. Fibrous Dust. Authors of Documents in Volume 8. Index.
- Volume
-
v .9 : gw ISBN 9783527270392
Description
The volumes of this series describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Several important carcinogens are treated separately. Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects on man, effects on animals, genotoxicity and carcinogenicity. Volume 9 contains 29 additional compounds, half of them metal-working fluid components.
Table of Contents
- Metal-working fluid components: 2-(2-aminoethoxy) ethanol, 1-amino-2-propanol, 2-amino-2-ethyl-1,3-propanediol, decyl oleate, 2-amino-2-methyl-1-propanol, bithionol, 1-hexanol, cloroacetamide-n-methylol, piperazine, triethylene glycol n-butyl ether
- chloroacetic acid methyl ester
- cholorpromazine
- diethylene glycol dimetyl ether
- hydrazobenzene
- nitrous oxide
- olaquindox.
- Volume
-
v. 10 : gw ISBN 9783527270415
Description
The volumes of this series present almost 300 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity, manifesto. Volume 10 contains 16 reviews, 3 of them on metal-working fluid components. From the contents: Ozone, Trichloroethylene, Cyclohexanone, o-Anisidine, 2-Chloroacrylonitrile, p-Chlorobenzotrichloride, Cobalt, Diethylene glycol, Ethylene, Hydroquinone, N-Methyl-2-pyrrolidone, Polyethylene glycol, Polypropylene glycol, Sodium pyrithione.
Table of Contents
o-Anisidine. 2-Chloroacrylonitrile. p-Chlorobenzotrichloride. Cobalt, its Alloys and Water-Soluble Salts. Cyclohexanone. 2,2-Dichloro-1,1,1-trifluoroethane. Diethylene Glycol. Ethylene. Hexahydrophthalic Anhydride/Methyltetrahydrophthalic Anhydride. Hydroquinone. N-Methyl-2-pyrrolidone (vapour). Ozone. Trichloroethylene. METAL-WORKING FLUID COMPONENTS. Polyethylene Glycol. Polypropylene Glycol. Sodium Pyrithione. Authors of Documents in Volume 10. Index.
- Volume
-
v. 12 : gw ISBN 9783527270439
Description
The volumes of this series present more than 300 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about topics such as toxic effects, modes of action, effects in man, and effects on animals.
Table of Contents
- Changes in the classification of carcinogenic chemicals in the work area - 2-aminoethanol
- 2-butanone
- n-butyl acrylate
- carbon disulfide
- chloroacetaldehyde
- chlorobenzene
- ethanol
- ethyl acetate
- piperazine
- 2-propoxyethanol
- 2-propoxyethyl acetate
- sodium hydroxide
- 2,4,5-trichlorophenol
- zirconium and its compounds
- dusts - general threshold limit value for dust
- aerosols dusts, fumes and mists
- manganese and its inorganic compounds.
- Volume
-
v. 13 : gw ISBN 9783527270477
Description
The volumes of this series present more than 300 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity, manifesto. The accumulated expertise of the Commission's toxicologists and occupational physicians makes their reviews invaluable for all involved in occupational health and safety.
Table of Contents
- GENERAL PAPERS Passive smoking CHEMICAL SUBSTANCES Acetic anhydride Ammonia Bisphenol A Boron oxide Boron trifluorid N--Carboxyanthranilic anhydride Cereal flour dusts rye and wheat Chlorinated naphthalenes 1--Chloro--2,4--dinitrobenzene Cumene Cyclohexane Diazomethane Diethylether Ethylene glycol dimethacrylate Ethylene oxide Hexone Hydrazine Hydrogen bromide 2--Hydroxyethyl methacrylate Methyl 2--cyanoacrylate and Ethyl 2--cyanoacrylate 2--Nitro--p-- phenylenediamine 1--Nitropropane o--Phenylenediamine TEDP 1,1,1,2--Tetrafluoroethane Triethylamine
- Woods: Acacia melanoxylon Bowdichia nitida Brya ebenus Dalbergia latifolia, D. melanoxylon, D. nigra, D. retusa, D. stevensonii Machaerium sceloxylon
- Volume
-
v. 14 : gw ISBN 9783527270507
Description
The volumes of this series present more than 300 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity, manifesto. The accumulated expertise of the Commission's toxicologists and occupational physicians makes their reviews invaluable for all involved in occupational health and safety.
Table of Contents
- GENERAL PAPERS
- The Relevance of Physical Activity for Inhalation Kinetics
- The Relevance of Hyperbaric Pressure for the Body Burden of Inhaled Gaseous Compounds
- CHEMICAL SUBSTANCES
- Chloroform
- Cresol (all Isomers)
- Diborane
- 1,2-Dibromo-2,4-Dicyanobutane
- 2-Diethylaminoethanol
- n-Hexane
- 1-Methoxy-2-Propanol
- 4,4'-Methylene Diphenyl Isocyanate (MDI) and "Polymeric MDI" (PMDI)
- 4-Nitrosophenol
- p-Phenylenediamine
- Thiourea
- Tin and Its Inorganic Compounds
- 1,2,4-Trichlorobenzene
- Turpentine
- Vinylcarbazole
- 4-Vinylcycohexene
- DUSTS
- Silica, Crystalline: Quartz Dust, Cristobalite Dust and Tridymite Dust (Respirable Fraction)
- WOODS
- Calocedrus Decurrens
- Chlorophora Excelsa
- Diospyros Species
- Distemonanthus Benthamianus
- Grevillea Robusta
- Mansonia Altissima
- Panatecoma Peroba
- Tabebuia Species
- Tectona Grandis
- Authors of Documents in Volume 14
- Index
- Volume
-
v. 15 : gw ISBN 9783527270514
Description
The volumes of this series present more than 300 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity, manifesto.
Table of Contents
- Acrylic acid polymer (neutralized, cross--linked)
- Allyl alcohol
- Arsine
- 1,3--Butadiene
- Butynediol
- g--Hexachlorocyclohexane (Lindane)
- Hexachlorobenzene
- Merbromin
- Mercury and inorganic mercury compounds
- Mercury compounds, organic
- Methanol
- a--Methyl styrene
- Natural rubber latex
- Rubber components
- Sulfuric acid
- Thimerosal
- Xylene (all isomers)
- Zinc chromate
- Volume
-
v. 16 : gw ISBN 9783527270521
Description
The volumes of this series present more than 300 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity, manifesto.
Table of Contents
- Acrolein
- n-Butyl acrylate
- Ethyl acrylate
- 2-Ethylhexyl acrylate
- Ethyl methacrylate
- Glutaraldehyde
- Hexachlorobenzene
- 2-Hydroxyethyl acrylate
- Hydroxypropyl acrylate (all isomers)
- 2-Hydroxypropyl methacrylate
- Lindane
- Methanol
- Methyl acrylate
- Methyl methacrylate
- Pentaerythritol triacrylate
- Trimethylolpropane triacrylate
- Metal-working fluid components
- Citric acid and its alkali metal salts
- 5-Ethyl-3,7-dioxa-1-azabicyclo[3.3.0]octane (EDAO)
- Hexylene glycol
- 3-Iodo-2-propynyl-N-butylcarbamate
- Isodecyl oleate
- 2-Octyl-4-isothiazolin-3-one
- Oleoyl sarcosine
- Dusts
- Aerosols - ultrafine aerosol particles, their aggregates and agglomerates
- Tantalum
- Wollastonite
- Volume
-
v. 17 : gw ISBN 9783527270552
Description
The volumes of this series present about 400 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity, manifesto.
Table of Contents
- General Papers
- Germ Cell Mutagens
- Chemical Substances
- Benzaldehyde
- Bitumen (vapour and aerosol)
- tert-Butyl methyl ether
- Dichloromethane
- Formaldehyde
- Lead and its inorganic compounds
- Oleic acid
- Phenyl isocyanate
- Picric acid
- Tributyl phosphate
- Turpentine
- Author of Documents in Volume 17
- Index
- Volume
-
v. 18 : gw ISBN 9783527277940
Description
The volumes of this series present about 400 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity, manifesto.
Table of Contents
Allyl chloride. Amitrole. Carbon black in the form of inhalable dust. Carbon tetrachloride. Coal mine dust. Diisobutyl ketone. Endrin. Furfural. Methyl acetate. 4,4'--Methylene--bis(2--methylaniline). Molybdenum and its compounds. Wood dust. Woods: Entandrophragma species. Woods: Gonystylus bancanus (Miq.) Baill. Woods: Khaya species. Woods: Quercus species. Woods: Swietenia species. Woods: Terminalia ivorensis A.Chev., Terminalia superba Engl. & Diels Woods: Thuja species. Woods: Tieghemella Africana A. Chev., Tieghemella heckelii Pierre. Woods: Triplochiton scleroxylon K. Schum. Zinc chloride and zinc chloride fume. Zinc oxide fume.Authors of Documents in Volume 18.Index.
- Volume
-
v. 19 : gw ISBN 9783527277964
Description
The volumes of this series present about 400 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database which determines the level of a MAK value (Maximum Concentrations at the Workplace). Each evaluation document is written to a standard format and includes sections about toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity, manifesto.
Table of Contents
Acetonitrile. Bisphenol A diglycidyl ether. n--Butyl acetate. sec--Butyl acetate. tert--Butyl acetate. n--Butyl alcohol. sec--Butyl alcohol. tert--Butyl alcohol. Demeton. 4,6--Dinitro--o--cresol. Ferbam. Formic acid. Formic acid ethyl ester. Furfuryl alcohol. Hydrogen cyanide, potassium cyanide and sodium cyanide. Isobutyl acetate. Isobutyl alcohol. Nitrobenzene. Nitroethane. Nitromethane. Rotenone. Strychnine. Toxaphene. Xylidine (isomers). Authors of Documents in Volume 19. Index.
- Volume
-
v. 20 : gw ISBN 9783527277971
Description
The volumes in this series present some 400 indispensable toxicological evaluation documents on important occupational toxicants and carcinogens. They describe the toxicological database that determines the level of a MAK value (Maximum Concentrations at the Workplace). Each document is written to a standard format and includes sections on toxic effects, modes of action, effects in man, effects on animals, genotoxicity and carcinogenicity.
Table of Contents
Butane (both isomers). 1,2--Dichlorobenzene. 1,4--Dichlorobenzene. Diethyl sulfate. 1,4--Dioxane. 2--Ethylhexanol. Glycidol. Ketene. Metal working fluids. Mothyl mercaptan. 1 --Octanol. Resorcinol. Sodium azide. Styrene. Toluene diisocyanate. Authors of Documents in Volume. Index.
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