Oral cancer : detection of patients and lesions at risk

著者

書誌事項

Oral cancer : detection of patients and lesions at risk

edited by N.W. Johnson

（Risk markers for oral diseases / edited by N.W. Johnson, v. 2）

Cambridge University Press, c1991

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注記

Includes index

Based on three symposia held in 1988/89; organized by the Section of Odontology of the Royal Society of Medicine

内容説明・目次

内容説明

Cancer of the oral and pharyngeal mucosae is a major public health problem in many parts of the world, and dental caries and periodontal diseases are almost universally prevalent. Nevertheless severe oral disease exists in only a minority of any population, and the three volumes comprising Risk Markers for Oral Diseases set out to characterise the at-risk groups and define markers by which they may be identified. Reviewing epidemiological, clinical and laboratory data, these volumes point the way towards improved diagnostic and prognostic testing, an exciting and rapidly expanding aspect of dentistry. Knowledge of the risk factors for oral cancer has lagged behind that for dental caries or periodontal diseases, and this volume provides a wide-ranging survey of the most promising fields of investigation. In addition to the well known aetiological role of tobacco and alcohol, leading research workers from both the dental and the basic sciences review the role of diet and nutrition, infective agents and immunological mechanisms in the genesis of oral cancer. The contribution of modern molecular and cell biology is authoritatively explored, and the scope for improved screening and prevention is an underlying theme throughout the book.

目次

  • Part I. How Great is the Risk?: 1. A global view of the epidemiology of oral cancer N. W. Johnson
  • Part II. Markers of the High Risk Patient: 2. Risk factors and risk markers for oral cancer in high incidence areas of the world D. K. Daftary, P. R. Murti, R. B. Bhonsle, P. C. Gupta, F. S. Mehta and J. J. Pindborg
  • 3. Risk factors and risk markers for oral cancer in low incidence areas of the world W. H. Binnie
  • 4. The Epstein-Barr virus in neoplasms of the head and neck G. De-The
  • 5. Evidence for infective agents in the aetiology of oral cancer C. Scully, S. S. Prime, M. F. Cox and N. J. Maitland
  • 6. Immune status in head and neck cancer, with special reference to cancer of the oral cavity S. G. Gangal and R. J. Tatake
  • Part III. Markers of the High Risk Lesion: 7. Clinical signs and symptoms of the high risk lesion M. Harris
  • 8. Structural indicators of the high risk lesion D. G. MacDonald and S. M. Saks
  • 9. Cytoplasmic markers of disturbed epithelial differentiation as markers of high risk lesions with special reference to cytokeratins P. R. Morgan, P. J. Shirlaw, E. B. Lane, I. M. Leigh and N. W. Johnson
  • 10. Cell surface carbohydrates in differentiation and malignant development of oral epithelium E. Dabelsteen, J. Reibel and H. Clausen
  • 11. Epithelial-mesenchymal interaction in tissue homeostasis and malignant transformation N. E. Fusenig, D. Breitkreutz, P. Boukamp, A. Bohnert and I. C. Mackenzie
  • 12. The biology of oncogenes and their role in malignant transformation J. K. Field
  • 13. Growth factors and their receptors as markers of the higher risk lesion, with special reference to epithelial growth factors A. A. Talacko, P. J. Shirlaw and N. W. Johnson
  • 14. Presence and expression of latent viruses in oral tissues N. J. Maitland, C. Lynas, T. Bromidge, I. Crane, S. R. Flint, M. F. Cox, S. S. Prime and C. Scully
  • 15. Human oral keratinocyte cultures and in vitro model systems for studying oral carcinogenesis S. E. Chang
  • Part IV. Implications of New and Existing Knowledge: 16. Implications for diagnosis, prognosis and patient management J. D. Langdon
  • 17. Public health aspects of oral cancer: implications for cancer prevention in the community J. J. Pindborg, D. K. Daftary, P. Gupta, M. B. Aghi, R. B. Bhonsle, P. R. Murti, F. S. Mehta and K. A. A. S. Warnakulasuriya
  • 18. Envoi: new knowledge concerning oral cancer and research priorities N. W. Johnson
  • Index.

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