Deafferentation pain syndromes : pathophysiology and treatment
Author(s)
Bibliographic Information
Deafferentation pain syndromes : pathophysiology and treatment
（Advances in pain research and therapy, v. 19）
Raven Press, c1991
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Includes bibliographical references and index
Description and Table of Contents
Description
This volume highlights advances in the understanding, diagnosis and treatment of chronic deafferentation pain syndromes, commonly associated with phantom limbs, paraplegia, peripheral nerve injuries and brachial plexus avulsion injuries. The contributors describe new research using animal models to study the neuroanatomy, neurophysiology, neurochemistry, neuropharmacology, and behavioural manifestations of deafferentiation pain. Noted experts detail new methods for distinguishing the pain of deafferentation from other painful processes and discuss current surgical and medical therapies for deafferentation pain syndromes.
Table of Contents
- Part 1 Neurobiology of deafferentation pains: neuroanatomy and neurophysiology - historical perspective of deafferentation in the work of Rolando and the discovery of the dorsal horn of the spinal cord, F. Caputi and E. de Divitiis, deafferentation effects on the developing trigeminal brainstem complex, M.F. Jacquin et al, mechanisms underlying deafferentation effects on the developing trigeminal brainstem complex, R.W Rhoades et al, abnormal anatomy of deafferentation - regeneration and sprouting within the central nervous system, E. Bullitt, central neurogenic pain - possible mechanisms, W.D. Willis, the neurophysiology of deafferentation syndromes, J. Ovelmen-Levitt, neurophysiological studies in rats deafferented by dorsal root sections, D. Albe-Fessard and O. Rampin, evidence that thalamus is involved in the generation of sensory abnormalities observed in human central pain syndromes, F.A. Lenz
- neurochemistry and neuropharmacology - the general aspects of neuropharmacology of dorsal horn function, B. Blumenkopf, synaptic transmission in the spinal dorsal horn, L. Urban, effects of changing ionic environments on reflex transmission in mouse spinal cord, G. Czeh, studies on the pharmacology of spinal systems underlying anomalous pain states, T.L. Yaksh and T. Yamamoto
- behaviour and deafferentation pains - the behavioural syndrome of deafferentation dysesthesias, M. Levitt, experimental animal models of chronic pain, E. Rossitch, Jr., chronic dysesthesias of central neural origin in subhuman primates, M. Levitt. Part 2 Clinical aspects of deafferentation pains: pathology and treatment - deafferentation pain syndrome - introduction, R.R. Tasker, deafferentation syndromes in humans - a general discussion, W.H. Sweet, the treatment of central deafferentation pain syndrome, C.A. Pagni, treatment of central deafferentation syndrome - thalamic syndrome, C. Sheiff, treatment of the deafferentation pain syndromes of the trigeminal system, C.E. Rawlings, III and R.H. Wilkins, paraplegia and pain, B.S. Nashold, Jr., treatment of deafferentation pains following peripheral nerve injury, A.H. Friedman, deafferentation syndrome - medical treatment, A. Tourian.
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