Manual of quantitative pathology in cancer diagnosis and prognosis

著者

書誌事項

Manual of quantitative pathology in cancer diagnosis and prognosis

J.P.A. Baak

Springer-Verlag, c1991

  • : gw
  • : us

タイトル別名

Quantitative pathology in cancer diagnosis and prognosis

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注記

Rev. and expanded version of: A manual of morphometry in diagnostic pathology. 1983

Includes bibliographical references and indexes

内容説明・目次

内容説明

Focusing on diagnostic protocols and quantitative work in the treatment of cancer, this volume covers the applications of flow cytometry, morphometry, digital image processing, artificial intelligence, laser microscopy, immunopathology and molecular biology.

目次

  • I: Theoretical Background.- 1 The Case for Morphometry in Diagnostic Pathology.- References.- 2 Diagnosis Making: Error Sources.- 2.1 The Problem.- 2.2 The Diagnosis Making Process.- 2.3 Morphological Facts.- 2.4 Stages in the Analytical Diagnostic Process.- 2.5 Error Sources in Diagnosis Making.- 2.6 Psychological Consequences.- 2.7 Summary.- References.- 3 Obtaining Quantitative Data.- 3.1 Quantitative Microscopy.- 3.2 Measurements in Tissue Sections: the Problem of Dimension Reduction.- 3.3 What is Stereology?.- 3.4 The Scope of Stereology and Planimetry.- 3.5 Counting of Elements - Mitotic Counts.- 3.6 The Historical Lines.- 3.7 Stereology and Morphometry.- 3.8 Scanning (Cyto)photometry.- 3.9 Flow Cyto(photo)metry.- 3.10 Digital Image (Picture) Processing.- References.- 4 Classification of New Cases: Some Aspects of Single and Multivariate Analysis.- 4.1 Introduction.- 4.2 The Problem of Overlap.- 4.3 Receiver Operating Characteristic Curve.- 4.4 Decision Rules.- 4.5 Decision Trees.- 4.6 Multivariate Analysis.- 4.7 Number of Features and Objects Used in the Analysis.- 4.8 Numerical Classification Probabilities.- 4.9 Non-linear Discriminant Analysis.- 4.10 Objectives of Decision Rules.- 4.11 Summary.- References.- 5 Structural Morphology.- 5.1 Introduction.- 5.2 The Structural Model.- References.- II: Applications of Morphometry in Diagnostic Pathology.- 6 Applications of Morphometry in Tumour Pathology.- 6.1 Introduction.- 6.2 Endometrium: Hyperplasia or Carcinoma.- References.- 6.3 Myometrium: Leiomyoma or Leiomyosarcoma.- References.- 6.4 Ovary: Borderline or Malignant Tumour.- References.- 6.5 Cervix: Squamous Cell Changes in Condyloma Acumination and Dysplasia.- References.- 6.6 Cervix: Adenocarcinoma in Situ.- References.- 6.7 Mesothelial Cells: Morphometric Distinction Between Benign and Malignant in Pleural Fluid.- References.- 6.8 Pleural Lesion: Histological Distinction Between Malignant Mesothelioma, Benign Lesion and Carcinoma Metastases by Morphometry.- References.- 6.9 Nasal Mucosa: Morphometry of Metaplastic, Dysplastic, and Carcinomatous Alterations in Nickel Workers.- References.- 6.10 Stomach: The Application of Morphometry in Gastric Cytological Diagnosis.- References.- 6.11 Bladder: Selection of Patients with Papillary T1 Tumours with a Poor Prognosis.- References.- 6.12 Thyroid: Morphometry for the Pre-operative Diagnosis of Follicular Adenoma and Carcinoma.- References.- 6.13 Central Nervous System: Grading of Astrocytomas Using Quantitative Microscopic Features.- References.- 6.14 Bone Tumours.- References.- 6.15 Spleen: Prediction of Spleen Involvement in Hodgkin's Disease.- References.- 6.16 Lymphomas: Morphometric Analysis of Large Cell Non-Hodgkin Lymphomas.- References.- 6.17 Cutaneous Lymphomas: The Importance of Morphometry in the Diagnosis of Mycosis Fungoides and Sezary's Syndrome.- References.- 6.18 Breast Lesions: Morphometry of Cytodiagnosis.- References.- 6.19 Breast Cancer: Correlation of Oestrogen Receptor and Morphometric Features.- References.- 6.20 Breast Cancer: Prediction of the Prognosis.- References.- 7 Applications of Morphometry in Non-tumour Pathology.- 7.1 Small Intestine: Morphometry of Biopsies for the Diagnosis of Food Allergy.- 7.2 Large Bowel: Differential Diagnosis of Inflammatory Diseases with Morphometry and Immunohistochemistry.- References.- 7.3 Pancreas: Island Volume in Diabetics and Controls.- References.- 7.4 Pancreas: Morphometric Evaluation of Cystic Fibrosis.- References.- 7.5 Placenta Morphometry.- References.- 7.6 Testis: Seminiferous Tubule Hypercurvature Syndrome.- References.- 7.7 Testis: Value of Morphometry in Predicting the Prognosis.- References.- 7.8 Kidney Morphometry.- References.- 7.9 Liver Morphometry.- References.- 7.10 Lung: Histomorphometry.- References.- 7.11 Bone Morphometry.- References.- 7.12 Muscle: Morphometric Analysis of Biopsies.- References.- III: Technical Aspects.- Addendum 1: Equipment for Quantitative Microscopy.- A.1.1 Introduction.- A.1.2 Description of Equipment.- A.1.3 Point Counting Equipment.- A.1.4 Graphic Tablets.- A.1.5 More Complicated Systems.- A.1.6 Photometry Microscopes.- A.1.7 TV Scanners.- A.1.8 Flow Cytophotometry.- Addendum 2: Practical Morphometry.- A.2.1 Stereology.- A.2.1.1 Introduction.- A.2.1.2 How Many Points Should be Counted?.- A.2.1.3 Optimizing the Efficiency of Point Counting.- A.2.2 Planimetry with a Graphic Tablet.- A.2.3 Morphometry of the Endometrium.- A.2.4 Morphometry of the Ovary.- A.2.5 Morphometry of the Nasal Mucosa.- A.2.6 Morphometry of the Thyroid.- A.2.7 Morphometry of the Spleen.- A.2.8 Morphometry of Large Cell Non-Hodgkin Lymphomas.- A.2.9 Morphometry of Breast Cancer.- A.2.9.1 Cytology.- A.2.9.2 Histology.- A.2.10 Morphometry of the Small Intestine.- A.2.11 Morphometry of the Large Intestine.- A.2.12 Morphometry of the Pancreas.- A.2.13 Morphometry of the Placenta.- A.2.13.1 Material.- A.2.13.2 Techniques.- A.2.14 Morphometry of the Testis.- A.2.15 Morphometry of the Kidney.- A.2.16 Morphometry of the Liver.- A.2.16.1 Ultrastructural Liver Morphometry.- A.2.16.2 Morphometry in Fulminant Livercell Insufficiency.- A.2.16.3 Morphometry of Chronic Persistent Hepatitis.- A.2.17 Practice of Morphometry of the Whole Lung.- A.2.18 Bone Morphometry.- References.- Addendum 3: Test Grids.- Addendum 4: Glossary.- Addendum 5: Recommended Books and Journals
  • Companies for Image Analysis Equipment.- Author Index.

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