Principles of nuclear magnetic resonance microscopy

著者

書誌事項

Principles of nuclear magnetic resonance microscopy

Paul T. Callaghan

Oxford University Press, 1991

  • pbk

大学図書館所蔵 件 / 全14件

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注記

Includes bibliographical references and index

内容説明・目次

巻冊次

ISBN 9780198539445

内容説明

Nuclear magnetic resonance imaging is best known for its spectacular use in medical tomography. However, the method has potential applications in biology, materials science and chemical physics, some of which have begun to be realized as laboratory NMR spectrometers have been adapted to enable small-scale imaging. NMR microscopy has available a variety of contrast including molecular specificity and sensitivity to molecular dynamics. In NMR imaging the signal is acquired in k-space, a dimension which bears a Fourier relationship with the positions of nuclear spins. A dynamic analogue of k-space imaging is the Pulsed Gradient Spin Echo (PGSE) experiment in which the signal is acquired in q-space, conjugate to the distances moved by the spins over a well-defined time interval. Q-space microsocpy provides images of the nuclear self-correlation function with a resolution some two orders of magnitude better than is possible in imaging the nuclear density. As well as revealing the spectrum of molecular motion, PGSE NMR can be used to study morphology in porous systems through the influence of motional boundaries. This book explores principles and common themes underlying these two variants of NMR Microscopy, providing many examples of their use. The methods discussed here are of importance in fundamental biological and physical research, as well as having applications in a wide variety of industries, including those concerned with petrochemicals, polymers, biotechnology, food processing and natural product processing.

目次

  • Principles of imaging
  • introductory nuclear magnetic resonance
  • the influence of magnetic field gradients
  • high resolution k-space imaging
  • k-space microscopy in biology and minerals science
  • the measurement of motion using spin echoes
  • structural imaging using q-space
  • spatially heterogeneous motion and dynamic NMR microscopy
  • elements of the NMR microscope.
巻冊次

pbk ISBN 9780198539971

内容説明

Nuclear Magnetic Resonance Imaging is best known for its spectacular use in medical tomography. However the method has potential applications in biology, materials science, and chemical physics, some of which have begun to be realized as laboratory NRM spectrometers have been adapted to enable small scale imaging. NMR microscopy has available a rich variety of contrast including molecular specificity and sensitivity to molecular dynamics. In NMR imaging the signal is acquired in k-space, a dimension which bears a Fourier relationship with the positions of nuclear spins. A dynamic analogue of k-space imaging is the Pulsed Gradient Spin Echo (PGSE) experiment in which the signal is acquired in q-space, conjugate to the distances moved by the spins over a well-defined time interval. q-space microscopy provides images of the nuclear self-correlation function with a resolution some two orders of magnitude better than is possible in imaging the nuclear density. As well as revealing the spectrum of molecular motion, PGSE NMR can be used to study morphology in porous systems through the influence of motional boundaries. This book explores principles and common themes underlying these two variants of NMR Microscopy, providing many examples of their use. The methods discussed here are of importance in fundamental biological and physical research, as well as having applications in a wide variety of industries, including those concerned with petrochemicals, polymers, biotechnology, food processing and natural product processing.

目次

  • Principles of imaging
  • Introductory nuclear magnetic resonance
  • The influence of magnetic field gradients
  • High resolution k-space imaging
  • k-space microscopy in biology and minerals science
  • The measurement of motion using spin echoes
  • Structural imaging using q-space
  • Spatially heterogeneous motion and dynamic NMR microscopy
  • Elements of the NMR microscope.

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