Bibliographic Information

Addictive states

editors, Charles P. O'Brien, Jerome H. Jaffe

(Research publications / Association for Research in Nervous and Mental Disease, v. 70)

Raven Press, c1992

Available at  / 5 libraries

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Note

Based on the 70th Annual Meeting of the Association for Research in Nervous and Mental Disease, held Nov. 30-Dec. 1, 1990 in New York City

Includes bibliographical references and index

Description and Table of Contents

Description

This volume highlights the most significant advances in the understanding and treatment of chemical dependence. Synthesizing basic and clinical research on cocaine, nicotine, cannabis, opiates, and alcohol, the contributors attempt to show how insights into the mechanisms of action of these drugs and the neural pathways of reward have been translated into improved treatment strategies. Key issues examined include brain mechanisms of drug-induced reinforcement, neuroendocrine systems involved in reinforcement, the role of drug receptors and endogenous ligands in addiction, the relationship of psychopathology to addiction, the neurological complications of substance abuse, the rationale for maintenance pharmacotherapy of opiate dependence, and the relative efficacy of treatments for dependence on alcohol and other drugs.

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